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Xifaxan (Rifaximin)
Xifaxan (Rifaximin)
Xifaxan, which contains the active component Rifaximin, is a ground-breaking antibiotic designed to treat some intestinal infections without having the extensive impacts on gut flora that antibiotics are known for. It’s your go-to treatment for non-systemic infections, providing comfort while prioritizing precision and safety.
Why Choose Xifaxan (Rifaximin)?
- Targeted Action: Works in the stomach to reduce systemic side effects.
- Low Absorption: Minimal absorption into the bloodstream, with a concentration on the infection site.
- Versatile: Effective in treating a variety of illnesses caused by bacterial infections of the intestines.
How to Use Xifaxan (Rifaximin)?
- For traveler’s diarrhea, use 200mg three times daily for three days.
- For IBS-D, take 550mg three times each day for fourteen days.
- For Hepatic Encephalopathy, take 550 mg twice a day.
Always follow the prescription supplied by your healthcare practitioner, since it will be tailored to your specific needs.
Important Safety Information about Xifaxan
- Pregnancy: There are no adequate or well-controlled trials in pregnant women. Use only when necessary and the possible benefit outweighs the risk to the fetus.
- Nursing Mothers: It is unclear whether rifaximin is excreted in human milk. When administering to a breastfeeding lady, proceed with caution.
- Pediatric use: Xifaxan’s safety and efficacy for various purposes have yet to be proven in patients under the age of 12.
- Drug Interactions: Inform your healthcare practitioner about all medications you use, including prescription and over-the-counter medications, vitamins, and herbal supplements. Xifaxan can interact with other medications and vice versa.
Fact Table
| Facts | Details |
| Generic Name | Rifaximin |
| Brand Names | Xifaxan |
| Drug Class | Antibiotic |
| FDA Approval | Yes |
| Indications | – Treatment of Irritable Bowel Syndrome with Diarrhea (IBS-D) in adults. – Reduction in the risk of overt hepatic encephalopathy (HE) recurrence in adults. – Treatment of travelers’ diarrhea caused by noninvasive strains of E. coli in adults and children at least 12 years old. |
| Dosage Forms | Tablet |
| Common Dosages | – IBS-D: 550 mg three times daily for 14 days. – HE: 550 mg twice daily. – Travelers’ diarrhea: 200 mg three times daily for 3 days. |
| Mechanism of Action | Rifaximin is a non-absorbable antibiotic that works by inhibiting the RNA synthesis in bacterial cells, leading to the death of bacteria. |
| Side Effects | – Nausea – Vomiting – Dizziness – Fatigue – Headache – Abdominal pain |
| Warnings and Precautions | – Risk of Clostridium difficile-associated diarrhea (CDAD) – Potential development of drug-resistant bacteria – Not effective for infections outside of the intestinal tract due to minimal systemic absorption |
| Interactions | – No major drug interactions due to minimal systemic absorption. However, always inform your healthcare provider about all medications you are taking. |
| Pregnancy Category | Not classified. Consult with a healthcare provider for advice. |
| Breastfeeding | Not known if rifaximin is excreted in human milk. Caution is advised. |
Common Side Effects
Like all medications, Xifaxan (Rifaximin) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Nausea
- Vomiting
- Dizziness
- Fatigue
- Headache
- Abdominal pain
If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Xifaxan (Rifaximin)?
You can order Xifaxan (Rifaximin) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
Product Review
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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