DDAVP (Desmopressin Acetate)
DDAVP (Desmopressin Acetate)
DDAVP (Desmopressin Acetate) is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. It is used to treat conditions characterized by excessive urination and has been a cornerstone in the management of diabetes insipidus and bedwetting (nocturnal enuresis) in children, as well as for managing symptoms of other conditions like hemophilia A and von Willebrand’s Disease (Type I) by increasing plasma levels of von Willebrand factor and factor VIII.
Why Choose DDAVP (Desmopressin Acetate)?
- Reduces Nighttime Urination: Effective in treating nocturnal enuresis, helping patients and families achieve better night sleep.
- Manages Diabetes Insipidus: Controls excessive thirst and urination caused by this condition.
- Supports Hemophilia A & von Willebrand’s Disease Patients: Enhances the body’s ability to manage bleeding by increasing certain clotting factors.
How to Use DDAVP (Desmopressin Acetate)?
- Ensure your healthcare provider is aware of all medications and supplements you are taking.
- Discuss your medical history, especially if you have conditions like cardiovascular disease or kidney issues.
- Confirm the diagnosis that DDAVP is intended to treat, such as diabetes insipidus, nocturnal enuresis, or a bleeding disorder.
- Nasal Spray: Follow the prescribed number of sprays in each nostril. Clear your nose before use. Tilt your head slightly forward, insert the nozzle into a nostril, and spray while breathing in gently through your nose.
- Oral Tablets: Take with or without food as directed by your healthcare provider, usually twice a day.
- Injectable Solution: Administered by a healthcare professional in a clinical setting.
Important Safety Information about DDAVP
- Contraindications: Not suitable for individuals with known hypersensitivity to desmopressin or any of the components of the formulation.
- Precautions: Should be used with caution in patients with cardiovascular disease or those at risk for fluid overload.
- Interaction: Inform your healthcare provider about all medications you are taking as DDAVP can interact with other drugs.
Fact Table
Facts | Details |
Generic Name | Desmopressin Acetate |
Brand Names | DDAVP, Minirin, Stimate, others |
Drug Class | Synthetic analog of vasopressin (antidiuretic hormone, ADH) |
FDA Approval | Yes (specific approval years vary by indication and form) |
Indications | – Diabetes insipidus – Nocturnal enuresis in children – Hemophilia A – Von Willebrand’s Disease (Type I) |
Forms Available | – Nasal spray – Oral tablets – Injectable solution |
How It Works | Mimics the action of antidiuretic hormone, reducing urine production and increasing clotting factors |
Common Side Effects | – Headache – Nausea – Mild abdominal cramps – Facial flushing – Nasal irritation (nasal spray form) |
Precautions | – Cardiovascular disease – Kidney disorders- Fluid intake restrictions |
Dosage | Varied based on condition, form of administration, and patient response |
Administration | Depends on the form (e.g., nasal spray, oral tablet, injection) |
Storage | Store at room temperature, away from light and moisture |
Interactions | Can interact with other medications affecting water/electrolyte balance, consult healthcare provider |
Common Side Effects
Like all medications, DDAVP (Desmopressin Acetate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Headache
- Nausea
- Mild abdominal cramps
- Facial flushing
- Nasal congestion or irritation (for nasal spray form)
- Sore throat (for nasal spray form)
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy DDAVP (Desmopressin Acetate)?
You can order DDAVP (Desmopressin Acetate) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.