DDAVP (Desmopressin Acetate)

DDAVP
Desmopressin Acetate

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Source:
DDAVP Injection
Desmopressin

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DDAVP Melt
Desmopressin

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Source:
Source:
DDAVP
Desmopressin Acetate

Source:
DDAVP Melt
Desmopressin

Source:
Generic Equivalents   What's the difference?
Desmopressin Acetate
Desmopressin Acetate

Source:
Source:
Generic Equivalents   What's the difference?
Desmopressin Acetate
Desmopressin Acetate

Source:
Source:

 

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DDAVP (Desmopressin Acetate)

DDAVP (Desmopressin Acetate) is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. It is used to treat conditions characterized by excessive urination and has been a cornerstone in the management of diabetes insipidus and bedwetting (nocturnal enuresis) in children, as well as for managing symptoms of other conditions like hemophilia A and von Willebrand’s Disease (Type I) by increasing plasma levels of von Willebrand factor and factor VIII.

Why Choose DDAVP (Desmopressin Acetate)?

  • Reduces Nighttime Urination: Effective in treating nocturnal enuresis, helping patients and families achieve better night sleep.
  • Manages Diabetes Insipidus: Controls excessive thirst and urination caused by this condition.
  • Supports Hemophilia A & von Willebrand’s Disease Patients: Enhances the body’s ability to manage bleeding by increasing certain clotting factors.

How to Use DDAVP (Desmopressin Acetate)?

  • Ensure your healthcare provider is aware of all medications and supplements you are taking.
  • Discuss your medical history, especially if you have conditions like cardiovascular disease or kidney issues.
  • Confirm the diagnosis that DDAVP is intended to treat, such as diabetes insipidus, nocturnal enuresis, or a bleeding disorder.
  • Nasal Spray: Follow the prescribed number of sprays in each nostril. Clear your nose before use. Tilt your head slightly forward, insert the nozzle into a nostril, and spray while breathing in gently through your nose.
  • Oral Tablets: Take with or without food as directed by your healthcare provider, usually twice a day.
  • Injectable Solution: Administered by a healthcare professional in a clinical setting.

Important Safety Information about DDAVP

  • Contraindications: Not suitable for individuals with known hypersensitivity to desmopressin or any of the components of the formulation.
  • Precautions: Should be used with caution in patients with cardiovascular disease or those at risk for fluid overload.
  • Interaction: Inform your healthcare provider about all medications you are taking as DDAVP can interact with other drugs.

Fact Table

 

Facts Details
Generic Name Desmopressin Acetate
Brand Names DDAVP, Minirin, Stimate, others
Drug Class Synthetic analog of vasopressin (antidiuretic hormone, ADH)
FDA Approval Yes (specific approval years vary by indication and form)
Indications – Diabetes insipidus – Nocturnal enuresis in children – Hemophilia A – Von Willebrand’s Disease (Type I)
Forms Available – Nasal spray – Oral tablets – Injectable solution
How It Works Mimics the action of antidiuretic hormone, reducing urine production and increasing clotting factors
Common Side Effects – Headache – Nausea – Mild abdominal cramps – Facial flushing – Nasal irritation (nasal spray form)
Precautions – Cardiovascular disease – Kidney disorders- Fluid intake restrictions
Dosage Varied based on condition, form of administration, and patient response
Administration Depends on the form (e.g., nasal spray, oral tablet, injection)
Storage Store at room temperature, away from light and moisture
Interactions Can interact with other medications affecting water/electrolyte balance, consult healthcare provider

Common Side Effects

Like all medications, DDAVP (Desmopressin Acetate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Headache
  • Nausea
  • Mild abdominal cramps
  • Facial flushing
  • Nasal congestion or irritation (for nasal spray form)
  • Sore throat (for nasal spray form)

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy DDAVP (Desmopressin Acetate)?

You can order DDAVP (Desmopressin Acetate) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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