Trulicity Pen (Dulaglutide)

Product Review


Trulicity
Dulaglutide

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Trulicity Pen (Dulaglutide)
Trulicity Pen (Dulaglutide)

Trulicity (Dulaglutide)

Trulicity (dulaglutide) is a once-weekly injectable prescription medication designed to help adults manage their Type 2 diabetes. As a glucagon-like peptide-1 (GLP-1) receptor agonist, Trulicity works by increasing insulin production in response to high blood sugar levels, slowing down the emptying of the stomach, and reducing the amount of sugar produced by the liver.

Why Choose Trulicity?

Trulicity mimics the action of the natural hormone GLP-1, which plays a crucial role in regulating blood sugar levels. When administered, Trulicity helps your body release more insulin when needed, which in turn lowers your blood sugar levels. Trulicity also helps reduce appetite and promotes weight loss in some patients.

How to use Trulicity?

Trulicity comes in a prefilled pen that is easy to use and requires no mixing or measuring. The medication is injected under the skin (subcutaneously) once a week, on the same day each week. It is important to follow your healthcare provider’s instructions on the dosage and administration of Trulicity. You can take Trulicity with or without food.

Important Safety Information Trulicity

Before starting Trulicity, inform your healthcare provider about any medical conditions you are taking, especially if you have a history of pancreatitis, kidney problems, or liver problems. Trulicity should not be used in patients with Type 1 diabetes or for the treatment of diabetic ketoacidosis. Pregnant or breastfeeding women should consult their healthcare provider before using Trulicity.

Fact Table for Trulicity

Fact Category Fact Details
Generic Name Dulaglutide
Drug Class Glucagon-like peptide-1 (GLP-1) receptor agonist
Uses Type 2 Diabetes management in adults
Administration Subcutaneous injection (under the skin)
Dosage Frequency Once a week
Drug Interactions May interact with other medications; inform healthcare provider about all medications, supplements, and herbal products being taken
Storage Conditions Store in the refrigerator between 36°F to 46°F (2°C to 8°C); do not freeze. In the refrigerator, Trulicity will last until the expiration date on the pen

Trulicity may be removed from the refrigerator and will last for 14 days

Common Side Effects of Trulicity

Some of the common side effects of Trulicity may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Decreased appetite

It’s essential to inform your healthcare provider about any side effects you experience while taking Trulicity.

How Can You Buy Trulicity (Dulaglutide)?

You can order Trulicity using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

Does Trulicity (Dulaglutide) work for weight loss?

Trulicity (Dulaglutide) approved for the management of Type 2 Diabetes, and does not have an indication for weight loss. However, some individuals with diabetes using Trulicity may experience weight loss as a secondary effect due to its potential to reduce appetite and promotion of a feeling of fullness. It is important to consult with a healthcare professional to determine the suitability of Trulicity for weight loss goals and to discuss potential risks and benefits.

Frequently Asked Questions

  1. References

    Trulicity [Package Insert]. Indianapolis, IN: Eli Lilly and Company; 2014

  2. What is the quantity of doses available in a Trulicity pen?

    Every Trulicity injection pen has the specific strength of medication you need for a week. You can get these pens in 0.75 mg, 1.5 mg, 3 mg, or 4.5 mg /0.5ml options. They’re typically sold in boxes containing four pens.

  3. Can Trulicity treatment continue indefinitely if needed?

    Trulicity is considered safe for long-term use. If you feel improvement after using Trulicity and not facing any severe side effects, you can continue using Trulicity for as long as you want. However, if you have a thyroid lump or you are suffering from nausea or low blood sugar, you should discontinue the medication.

  4. Is it safe to consume alcohol while on Trulicity treatment?

    Consuming alcohol can increase the risk of hypoglycemia (low blood sugar) in patients. Therefore it’s advisable for patients to restrict their alcohol intake to avoid the risk of hypoglycemia.

  5. Is constipation a common side effect of Trulicity?

    It’s quite common to experience stomach discomfort and constipation while using Trulicity. If you have any worries or significant stomach-related issues once you start taking Trulicity, it’s important to discuss it with your doctor.

  6. How to store Trulicity?

    It is recommended to keep Trulicity in the refrigerator, but if you need to travel or can’t refrigerate it for up to 14 days, it’s okay to store it at room temperature below 86°F (30°C). Just make sure to protect it from heat sources and light.

  7. What is the preferred site for giving a Trulicity injection?

    The usual spots for Trulicity injection are the back of the upper arms, the belly, or the top and outer parts of the thighs.It must be injected just under the skin into the fatty layer.

  8. Is there any risk of high blood pressure while using Trulicity?

    Research has shown that Trulicity is beneficial for patients having high blood pressure. However, if you notice any unusual changes in your blood pressure after starting Trulicity, it’s important to talk to your doctor.

  9. Is fatigue a common side effect of Trulicity?

    Using Trulicity can make you feel tired sometimes. Normally, for most people, these side effects usually get better within two to four weeks.

  10. How long does the effect of Trulicity last in your system?

    The half life of trulicity is 5 days. This means that after 5 days only half of the dose will be left in the system and therefore will no longer have an effect on blood glucose control. Once you’ve had your last Trulicity injection, it typically takes around 25 days for the medication to completely leave your body.

  11. What are the dietary guidelines for avoiding certain foods while on Trulicity?

    Trulicity can sometimes cause stomach discomfort, diarrhea, or constipation. To minimise these side effects, it is recommended to eat smaller and more frequent meals, avoiding high fat foods, etc.

  12. How much time does Trulicity take to show its effects?

    The effectiveness of Trulicity can vary among patients due to several factors. Nevertheless, many individuals who initiate Trulicity treatment observe improvements in their blood glucose levels within approximately four weeks. However, it may take several more weeks before the full benefits of Trulicity become completely apparent.

  13. Can Trulicity be characterized as an insulin drug?

    Trulicity is not a type of insulin. It is a GLP-1 agonist which works by stimulating glucose-dependent insulin from the pancreas and inhibiting glucagon.

  14. Does Trulicity help in weight loss?

    Trulicity is a non-insulin medication primarily intended for controlling blood glucose levels, not for weight loss. It is considered a weight loss neutral medication. However, as it helps stabilise blood sugar and often accompanies recommendations for regular exercise and healthier eating habits, patients can lose weight as they get their diabetes controlled.

  15. Are Trulicity and Ozempic similar medications?

    Trulicity and Ozempic are both non-insulin medications designed to regulate blood glucose levels in patients. Both medications are within a family of medications called GLP-1 agonists. While their active ingredients differ, they have similar mechanisms of action. Ozempic has demonstrated greater weight loss and more effective reduction in blood glucose levels compared to Trulicity in patients.

  16. Is Trulicity meant for long-term treatment?

    Yes, it is prescribed by the doctors for long-term treatment.

  17. What should I do if I miss a dose of Trulicity?

    If you miss a dose, you can inject the missed dose as long as there are at least 72 hours (3 days) or more before their next scheduled dose. However, if their next Trulicity dose is scheduled within less than three days (or 72 hours), it’s advised to skip the missed dose and proceed with the upcoming dose as usual.

  18. What to do if I overdose on Trulicity?

    In case of an overdose or severe symptoms like loss of consciousness or breathing difficulties, you should immediately seek emergency medical help or contact poison control at 1-800-222-1222 without any delay.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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