Trifexis (Spinosad/Milbemycin Oxime)
Trifexis (Spinosad/Milbemycin Oxime)
Trifexis is a powerful combination of Spinosad and Milbemycin Oxime designed to protect your dog from multiple parasites in one convenient tablet. Spinosad targets and kills adult fleas, working within 30 minutes and achieving complete effectiveness within hours. Milbemycin Oxime targets internal parasites, preventing heartworm disease and treating and controlling hookworms, roundworms, and whipworms. Together, they provide comprehensive, fast-acting protection to keep your dog healthy and parasite-free.
Why Choose Trifexis (Spinosad/Milbemycin Oxime)?
- Fast Flea Control: Starts killing fleas within 30 minutes, with full protection achieved within hours.
- Heartworm Prevention: Effectively prevents heartworm disease when administered as directed.
- Internal Parasite Control: Treats and controls hookworms, roundworms, and whipworms.
- Convenient Administration: Monthly oral tablet means no messy applications or need for additional products.
- Comprehensive Protection: Ideal for protecting against both internal and external parasites.
How to Use Trifexis (Spinosad/Milbemycin Oxime)?
- Administer with Food: Give Trifexis with a full meal to increase absorption.
- Monthly Dosage: Administer one tablet every 30 days for consistent protection.
- Weight-Based Dosage: Use the correct dosage based on your dog’s weight to ensure effectiveness and safety.
- Supervise Initial Dose: Observe your dog for a short period after the first administration to monitor for any reactions.
- Regular Schedule: Use Trifexis consistently, even during colder months, for ongoing protection.
Important Safety Information about Trifexis
- Storage: Store at room temperature, away from moisture and direct sunlight.
- Precautions: Only for use in dogs over 8 weeks of age and weighing at least 5 pounds. Not safe for cats.
- Consultation: Speak with a veterinarian before use, especially if your dog has a history of seizures or is currently on other medications.
- Avoid Overdosing: Follow dosing instructions carefully; do not administer more than once monthly.
Fact Table
| Facts | Details |
| Brand Name | Trifexis |
| Active Ingredients | Spinosad and Milbemycin Oxime |
| Purpose | Oral monthly tablet to prevent and treat flea infestations, heartworm disease, and intestinal parasites in dogs. |
| Uses | – Kills adult fleas and prevents flea infestations – Prevents heartworm disease – Treats and controls hookworm, roundworm, and whipworm infections |
| Mechanism of Action | – Spinosad: Targets flea nervous system, causing paralysis and death within hours. – Milbemycin Oxime: Disrupts nerve transmission in parasites, leading to their death. |
| Dosage Form | Oral chewable tablet |
| Recommended For | Dogs only (do not administer to cats) |
| Age Requirement | Safe for use in dogs aged 8 weeks and older |
| Weight Requirement | Suitable for dogs weighing 5 pounds or more |
| Administration Frequency | Once monthly (every 30 days) |
| Administration Method | Administer orally, with food, to ensure maximum absorption |
| Onset of Action | Begins killing fleas within 30 minutes of administration |
| Duration of Action | Protects against fleas, heartworms, and intestinal worms for 30 days |
| Storage Instructions | Store at room temperature, below 77°F (25°C); avoid exposure to excessive moisture and light |
| Safety Precautions | – For dogs only; do not use in cats.
– Consult a veterinarian if your dog has a history of seizures or neurological disorders. |
| Common Side Effects | – Vomiting – Lethargy – Diarrhea – Itching – Loss of appetite |
| Prescription Required | Yes, available only by prescription from a licensed veterinarian. |
Common Side Effects
Like all medications, Trifexis (Spinosad/Milbemycin Oxime) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Vomiting, especially if not given with food
- Lethargy or decreased activity
- Diarrhea
- Itching or mild skin reactions
- Loss of appetite
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Trifexis (Spinosad/Milbemycin Oxime)?
You can order Trifexis (Spinosad/Milbemycin Oxime) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
