Trelegy Ellipta (Fluticasone Furoate/Umeclidinium Bromide/Vilanterol Trifenatate)

Trelegy Ellipta
Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate

Trelegy Ellipta
Fluticasone Furoate, Umeclidinium Bromide, Vilanterol Trifenatate


Trelegy Ellipta (Fluticasone Furoate/Umeclidinium Bromide/Vilanterol Trifenatate)



Trelegy Ellipta(UMECLIDINIUM BROMIDE/FLUTICASONE FUROATE/ / VILANTEROL TRIFENATATE) is an inhalation powder medicine. It is a prescription drug. Moreover, it is used to make breathing easier and reduce flare-ups in patients with Chronic Obstructive Pulmonary Disease like Chronic bronchitis and Emphysema. It is a combination of 3 drugs, i.e. Fluticasone Furoate, Umeclidinium Bromide, and Vilanterol Trifenatate.

How It Works

Fluticasone Furoate belongs to a class of drugs called steroids. Moreover, it works by controlling the substance, which causes inflammation in the body. Umeclidinium Bromide belongs to a class of medications called anticholinergics. It helps to stop the muscles around the airways from contracting and expanding the airways, likewise. Vilanterol Trifenatate belongs to a class of drugs called bronchodilators. It helps to open the air passages in the lungs. This is how, by combining these drugs, Trelegy Ellipta helps the patients to improve their breathing.


  • However, not approved for children under 18 years.
  • Adult dosage:
  • Moreover, one inhalation orally once a day.
  • The maximum recommended dose is 1 inhalation in 24 hours, likewise.
  • No dose adjustment (normal dose) for senior patients, patients with renal impairment and patients with moderate liver problems, likewise.

Common Side Effects

  • Serious Side effects: for example,
  • Allergic reaction
  • Fungal infection in the mouth or throat
  • Pneumonia
  • Heart problems: Symptoms are, for instance:
  1. Chest pain
  2. High blood pressure
  3. Irregular heartbeat
  • Severe Breathing problems
  • Tremors and nervousness
  • Acute narrow-angle glaucoma: Symptoms are, for instance:
  1. Eye pain or swelling
  2. Discomfort
  3. Blurred vision
  • Hormonal disorder
  • Painful urination
  • High blood sugar
  • Low potassium level: Symptoms are, for instance:
  1. Leg cramps
  2. Constipation
  3. Numbness and weakness
  • Common Side effects: for example,
  • Cold
  • Nausea or vomiting
  • Stomach pain
  • Headache
  • Change in taste
  • Joint pain
  • Constipation or diarrhea

These are some side effects of this drug. However, if you notice any symptoms, call for immediate medical help.

How to Take This Medication

  • Use this medication as and when prescribed by the doctor, likewise.
  • Follow all the instructions and directions carefully, above all.
  • Use it only once in 24 hours, consequently.
  • Ask the doctor how to use the inhaler, if you don’t understand.
  • Prime the inhaler before use.
  • Use the inhaler carefully.
  • Rinse your mouth after use.
  • Clean the inhaler, too.
  • If you miss a dose, don’t take 2 doses at once.
  • If you overdose, get immediate medical help.

Warnings and Precautions

  • Important Warning:
  • Risk of death in asthma patients: The medication, however, increases the risk of death in asthma patients.
  • Other Warnings and Precautions:
  • Don’t take this medicine if you have/are, for instance:
  1. Allergic reaction
  2. Asthma
  • Inform the doctor if you have/are, for instance:
  1. Heart disease
  2. High blood pressure
  3. Weak immune system
  4. Fungal, bacterial, or viral infection due to parasites
  5. Liver disease
  6. Glaucoma
  7. Seizure
  8. Diabetic ketoacidosis
  9. Thyroid problems
  10. Bladder or urination problems
  11. Osteoporosis
  12. Pregnant or planning to get pregnant
  13. Breastfeeding
  14. Taking other medication, likewise
  15. Going to have surgery, moreover
  • It is not a rescue medicine. However, it will not work during a bronchospasm attack.
  • It is not approved for children under 18 years, above all.

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.

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