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Nexgard Chew (Afoxolaner)
Nexgard Chew (Afoxolaner)
Nexgard Chew (Afoxolaner), is a veterinarian-recommended oral medication designed to protect dogs from flea and tick infestations. Once ingested, Afoxolaner quickly absorbs into the bloodstream, targeting and disrupting the nervous systems of parasites, causing paralysis and death within hours.
Why Choose Nexgard Chew (Afoxolaner)?
- Provides fast-acting, monthly protection against fleas and ticks.
- Prevents flea infestations by killing adult fleas before they can lay eggs.
- Effective against common tick species, helping to reduce the risk of Lyme disease and other tick-borne illnesses.
- Easy-to-administer, beef-flavored chew that most dogs find palatable.
- Safe for puppies over 8 weeks old and weighing at least 4 pounds.
How to Use Nexgard Chew (Afoxolaner)?
- Administer once a month as a single chewable tablet with or without food.
- Offer the chew directly to your dog; if needed, it can be broken and mixed with food, ensuring the entire dose is consumed.
- Make sure to follow the dosage instructions based on your dog’s weight.
- Repeat monthly for continuous protection, setting a reminder to maintain consistency.
Important Safety Information about Nexgard Chew
- Store Nexgard Chews at room temperature, away from moisture and direct sunlight.
- Keep out of reach of children and other animals to avoid accidental ingestion.
- Consult your veterinarian before use, especially if your dog is pregnant, nursing, or has a history of seizures or neurological conditions.
- Do not use it on cats or other pets.
Fact Table
| Facts | Details |
| Product Name | Nexgard Chew |
| Active Ingredient | Afoxolaner |
| Formulation | Chewable tablet |
| Product Type | Oral flea and tick treatment |
| Purpose | Kills adult fleas and ticks, including black-legged tick, American dog tick, brown dog tick, and lone star tick |
| Mechanism of Action | Afoxolaner is an isoxazoline class compound that interferes with the nervous system of parasites by blocking GABA-gated chloride channels, causing death |
| Onset of Action | Begins killing fleas within 4 hours and ticks within 24 hours after administration |
| Duration of Effectiveness | 1 month (30 days) |
| Indications | For dogs and puppies 8 weeks of age or older, weighing at least 4 pounds |
| Usage Frequency | Monthly (every 30 days) |
| Key Benefits | – Fast-acting, starts working within 4 hours on fleas – Kills fleas before they can lay eggs – Effective against multiple tick species |
| Administration Instructions | Offer Nexgard as a treat to your dog, ensuring the entire dose is consumed. Safe to administer with or without food. |
| Safety Profile | Approved by FDA, suitable for puppies over 8 weeks old and dogs weighing at least 4 pounds |
| Storage Instructions | Store at room temperature (below 86°F/30°C) |
| Precautions | – Consult a vet before using in dogs with a history of seizures – Avoid using in pregnant or lactating dogs unless advised by a veterinarian |
| Side Effects | Possible side effects include vomiting, diarrhea, dry or flaky skin, and lethargy |
| Availability | Prescription-only product, available through veterinarians or licensed retailers |
Common Side Effects
Like all medications, Nexgard Chew (Afoxolaner) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Vomiting
- Diarrhea
- Dry or itchy skin
- Lethargy
- Reduced appetite
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Nexgard Chew (Afoxolaner)?
You can order Nexgard Chew (Afoxolaner) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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