Tecfidera (Dimethyl Fumarate)

Frequently Asked Questions

1. What is Tecfidera used for?

   Tecfidera is used to treat relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. It helps reduce the frequency of flare-ups and slow the progression of physical disability.

2. How does Tecfidera work?

   Tecfidera is believed to work by reducing inflammation and preventing nerve damage in the brain and spinal cord. Although the exact mechanism is not fully understood, it is thought to involve modulation of the immune system to decrease the activity of MS.

3. What are the common side effects of Tecfidera?

   Common side effects include flushing, redness, itching, or a burning sensation on the skin, as well as stomach pain, nausea, vomiting, diarrhea, and indigestion. Should you experience any adverse effects, promptly contact your physician.

4. Can Tecfidera cause weight changes?

   While weight gain or loss is not a commonly documented side effect of Tecfidera, some patients have reported weight fluctuations. It’s important to monitor any significant changes and discuss them with your doctor.

5. Can I drink alcohol while taking Tecfidera?

   Though alcohol does not interact directly with Tecfidera, avoiding heavy alcohol consumption is advised because it may elevate the risk of stomach irritation or other side effects. Drinking alcohol in moderation, with some time between your Tecfidera dose and alcohol intake, is generally considered safe.

6. How long does it take for Tecfidera to start working?

   Tecfidera may start to show effects within 24 weeks, but it can take up to two years to experience the full benefits. It’s important to continue taking the medication as prescribed, even if you do not notice immediate improvements.

7. Can I stop taking Tecfidera abruptly?

   Unlike some other MS medications, stopping Tecfidera abruptly does not typically lead to rebound disease activity. However, any decision to stop or change medication should be made in consultation with your healthcare provider.

8. Does Tecfidera interact with other medications?

   Tecfidera may interact with other drugs that affect the immune system or increase infection risk, such as natalizumab or rituximab. Always inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions.

9. Is Tecfidera safe to use during pregnancy or breastfeeding?

   Tecfidera should only be used during pregnancy if clearly needed, as the effects on the unborn baby are not fully known. It is also unknown if Tecfidera passes into breast milk, so consult your doctor before breastfeeding while on this medication.