Tecfidera (Dimethyl Fumarate)
Tecfidera (Dimethyl Fumarate)
Tecfidera (Dimethyl Fumarate) is an oral medication designed for the treatment of relapsing forms of multiple sclerosis (MS). This innovative treatment works by reducing inflammation and protecting nerve cells, helping to manage symptoms and reduce the frequency of relapses. Tecfidera offers a convenient twice-daily dosing schedule, providing a practical solution for individuals seeking to manage their MS effectively.
Why Choose Tecfidera (Dimethyl Fumarate)?
- Reduces MS Relapses: Tecfidera has been shown to significantly decrease the number of relapses in patients with relapsing forms of multiple sclerosis.
- Slows Disease Progression: Helps in slowing down the progression of physical disability associated with MS.
- Convenient Oral Administration: Easy-to-take capsule form, administered twice daily.
- Neuroprotective Properties: Protects nerve cells from damage by modulating the immune response.
- Proven Efficacy: Supported by clinical trials demonstrating its effectiveness in managing MS symptoms and progression.
How to Use Tecfidera (Dimethyl Fumarate)?
- Consult Your Healthcare Provider: Before starting Tecfidera, discuss your medical history and any other medications you are taking with your doctor.
- Follow Dosage Instructions: Take the medication exactly as prescribed by your healthcare provider. Typically, Tecfidera is taken twice daily with food to reduce the likelihood of gastrointestinal side effects.
- Swallow Whole: Do not crush, chew, or sprinkle the contents of the capsule.
- Regular Monitoring: Schedule regular check-ups with your doctor to monitor your response to the treatment and adjust dosages if necessary.
- Report Side Effects: Inform your healthcare provider about any side effects or adverse reactions you experience.
Important Safety Information about Tecfidera
- Allergic Reactions: Seek immediate medical attention if you experience symptoms of a severe allergic reaction, such as rash, itching, swelling, severe dizziness, or trouble breathing.
- Infections: Tecfidera may lower your white blood cell count, potentially increasing the risk of infections. Inform your doctor if you develop any signs of infection, such as fever, chills, or persistent sore throat.
- Liver Function: Periodic liver function tests may be recommended, as Tecfidera can affect liver enzymes.
- Flushing: Some patients may experience flushing (redness, warmth, itching, or burning sensation). This is usually mild to moderate and often decreases over time.
Fact Table
Facts | Details |
Brand Name | Tecfidera |
Generic Name | Dimethyl Fumarate |
Drug Class | Disease-modifying therapy (DMT) for Multiple Sclerosis |
Indication | Treatment of relapsing forms of multiple sclerosis (MS) |
Mechanism of Action | Reduces inflammation and prevents immune cells from attacking nerves by activating the Nrf2 pathway |
Dosage Form | Oral capsules |
Strengths Available | 120 mg and 240 mg capsules |
Usual Dosage | – Initial: 120 mg twice daily for 7 days – Maintenance: 240 mg twice daily |
Administration | Taken orally, with or without food; taking with food may reduce gastrointestinal side effects |
Key Benefits | – Reduces frequency of MS relapses – Slows progression of physical disability – Oral administration provides convenience |
Common Side Effects | – Flushing – Abdominal pain – Diarrhea – Nausea – Upper respiratory tract infections |
Contraindications | Known hypersensitivity to dimethyl fumarate or any of the excipients in Tecfidera |
Special Precautions | – Monitor liver function tests – Regular blood tests to check lymphocyte counts – Caution in patients with a history of severe infection |
Drug Interactions | Avoid use with other immunomodulating therapies and live vaccines |
Pregnancy Category | Category C (Risk cannot be ruled out; use only if benefits justify the potential risks) |
Storage | Store at room temperature (20°C to 25°C or 68°F to 77°F) |
Approval Date | Approved by FDA in March 2013 |
Common Side Effects
Like all medications, Tecfidera (Dimethyl Fumarate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Flushing
- Abdominal pain
- Diarrhea
- Nausea
- Upper respiratory tract infections
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Tecfidera (Dimethyl Fumarate)?
You can order Tecfidera (Dimethyl Fumarate) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
Frequently Asked Questions
- Is Tecfidera safe to use during pregnancy or breastfeeding?
- Does Tecfidera interact with other medications?
- Can I stop taking Tecfidera abruptly?
- How long does it take for Tecfidera to start working?
- Can I drink alcohol while taking Tecfidera?
- Can Tecfidera cause weight changes?
- What are the common side effects of Tecfidera?
- How does Tecfidera work?
- What is Tecfidera used for?