Tagrisso (Osimertinib)
Tagrisso (Osimertinib)
Tagrisso (Osimertinib) is a cancer therapy designed for patients with specific types of non-small cell lung cancer (NSCLC). As a third-generation tyrosine kinase inhibitor (TKI), Tagrisso selectively inhibits the epidermal growth factor receptor (EGFR) with T790M mutation, providing an effective treatment option for patients who have developed resistance to earlier-generation EGFR inhibitors.
Why Choose Tagrisso (Osimertinib)?
- Targeted Treatment: Specifically designed to target and inhibit the EGFR T790M mutation, ensuring precision therapy.
- Improved Survival Rates: Demonstrates a significant improvement in progression-free survival (PFS) compared to previous treatments.
- Brain Penetration: Effective in treating brain metastases due to its ability to cross the blood-brain barrier.
- Convenient Oral Administration: Administered as a once-daily oral tablet, simplifying the treatment regimen.
- Enhanced Quality of Life: Helps in managing symptoms and improving patients’ overall quality of life.
How to Use Tagrisso (Osimertinib)?
- Consult Your Oncologist: Ensure a qualified healthcare provider prescribes Tagrisso.
- Follow Dosage Instructions: Take the exact dosage as directed by your doctor, typically once daily.
- Do Not Crush or Split Tablets: Swallow the tablet whole with water; do not crush, split, or chew.
- Regular Monitoring: Attend all scheduled appointments for blood tests and scans to monitor the treatment’s progress.
- Manage Side Effects: Report any side effects to your healthcare provider promptly.
- Store Properly: Keep Tagrisso in its original packaging at room temperature, away from moisture and heat.
- Adherence: Do not miss doses. If a dose is missed, take it as soon as you remember unless it is almost time for the next dose.
Important Safety Information about Tagrisso
- Allergies: Inform your doctor of any allergies, especially to Osimertinib or any other medications.
- Medical History: Disclose your complete medical history, particularly any history of lung or breathing problems, heart issues, or liver disease.
- Pregnancy and Breastfeeding: Avoid use if you are pregnant or breastfeeding. Discuss potential risks with your doctor.
- Drug Interactions: Inform your healthcare provider about all other medications and supplements you are taking to avoid potential interactions.
Fact Table
| Facts | Details |
| Product Name | Tagrisso (Osimertinib) |
| Drug Class | Tyrosine Kinase Inhibitor (TKI) |
| Indications | Non-Small Cell Lung Cancer (NSCLC) with EGFR mutations |
| Mechanism of Action | Inhibits EGFR (Epidermal Growth Factor Receptor) tyrosine kinase, including T790M mutation, leading to inhibition of tumor cell growth |
| Dosage Form | Tablet |
| Strengths Available | 40 mg, 80 mg |
| Administration | Oral, once daily, with or without food |
| Common Side Effects | – Diarrhea – Rash – Dry skin – Nail toxicity – Cough |
| Contraindications | – Known hypersensitivity to osimertinib or any of its components |
| Monitoring Parameters | – Lung function (for interstitial lung disease) – ECG (for QT prolongation) – Ejection fraction (for cardiomyopathy) – Eye exams (for keratitis) |
| Special Populations | – Pregnancy: Can cause fetal harm – Breastfeeding: Not recommended – Pediatric: Safety and efficacy not established |
| Storage | Store at room temperature (20-25°C or 68-77°F), protect from moisture |
| Important Notes | – Regular follow-up and monitoring are essential – Report any unusual symptoms or side effects to your healthcare provider immediately |
Common Side Effects
Like all medications, Tagrisso (Osimertinib) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Diarrhea
- Rash
- Dry skin
- Nail toxicity
- Cough
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Tagrisso (Osimertinib)?
You can order Tagrisso (Osimertinib) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
