Synvisc (Hylan G-F 20)
Synvisc (Hylan G-F 20)
Synvisc (Hylan G-F 20) is a leading injectable treatment designed to provide up to six months of pain relief from knee osteoarthritis. It is specifically formulated to mimic the body’s synovial fluid, which lubricates and cushions the knee joint. Synvisc is a safe, effective, and minimally invasive option for those seeking to reduce the discomfort caused by osteoarthritis and improve their joint mobility.
Why Choose Synvisc (Hylan G-F 20)?
- Long-Lasting Relief: Provides pain relief for up to six months.
- Mimics Natural Fluid: Formulated to closely replicate the knee’s natural synovial fluid.
- Non-Surgical: A non-surgical treatment option that can be administered in a clinic setting.
- Improves Mobility: Helps restore natural joint function and mobility.
How to Use Synvisc (Hylan G-F 20)?
- Before the injection, the knee area is usually cleaned, and a local anesthetic may be applied to minimize discomfort during the procedure. Sometimes, excess fluid will be removed from the knee joint to prepare for the injection.
- Synvisc is administered as an intra-articular injection, meaning it’s injected directly into the knee joint.
- The typical regimen consists of three injections spaced one week apart. However, some formulations of Synvisc may allow for a single injection.
- The procedure is quick, generally taking only a few minutes.
- Patients are often advised to rest the knee and avoid strenuous activities for 24 to 48 hours after each injection to allow the joint to stabilize.
- Ice may be applied to the knee to help reduce swelling and discomfort.
Important Safety Information about Synvisc
- Initially, consult with your healthcare provider to determine if Synvisc is suitable for your condition. Your medical history, current health status, and the severity of your osteoarthritis will be evaluated.
- Serious side effects are rare but can include allergic reactions, infection, or knee joint inflammation.
- Synvisc should not be injected into patients with infections or skin diseases around the injection area.
- If the treatment is effective, it can be repeated every six months or as recommended by the healthcare provider.
Fact Table
| Facts | Details |
| Generic Name | Hylan G-F 20 |
| Brand Name | Synvisc |
| Classification | Viscosupplement |
| FDA Approval | Approved for use in treating osteoarthritis of the knee |
| Indications | Treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen |
| Administration | Intra-articular injection |
| Dosage Form | Injectable gel |
| Common Dosage | Typically administered as three injections, each one week apart. Single-injection formulas are also available |
| Mechanism of Action | Supplements the viscous properties of the synovial fluid in the knee, reducing pain and improving mobility |
| Common Side Effects | Pain, swelling, heat, redness at the injection site |
| Contraindications | Patients with infections or skin diseases in the area to be injected, allergies to avian proteins, feathers, or egg products |
| Special Considerations | Not a cure for osteoarthritis; effects are temporary and treatment might need to be repeated every six months |
Common Side Effects
Like all medications, Synvisc (Hylan G-F 20) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Pain
- Swelling
- Heat
- Redness in the knee joint after injection
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Synvisc (Hylan G-F 20)?
You can order Synvisc (Hylan G-F 20) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.

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