Septra DS (Sulfamethoxazole/Trimethoprim)

Septra DS
Sulfamethoxazole, Trimethoprim

Source:
Septra
Sulfamethoxazole, Trimethoprim

Source:
Generic Equivalents   What's the difference?
Sulfamethoxazole/Trimethoprim DS
Sulfamethoxazole, Trimethoprim

Source:

Septra DS (Sulfamethoxazole/Trimethoprim)

Septra DS (Sulfamethoxazole/Trimethoprim) is a powerful antibiotic combination that combats germs in your body, offering a two-pronged approach to treating bacterial infections. It is used to treat a wide range of bacterial infections, including urinary tract infections, respiratory infections, and specific forms of diarrhea. Septra DS is noted for its effectiveness in situations where other antibiotics may fail.

Why Choose Septra DS (Sulfamethoxazole/Trimethoprim)?

  • Dual-action formula:Combines Sulfamethoxazole with Trimethoprim to provide a more effective treatment for bacterial infections. 
  • Broad-spectrum antibiotics are effective against a large variety of microorganisms. 
  • Convenient dosing: Usually taken twice a day. 

How to Use Septra DS (Sulfamethoxazole/Trimethoprim)?

  • Dosage:Take exactly as directed by your healthcare provider. Do not consume greater or fewer amounts or for longer than recommended. 
  • Administration:May be taken with or without food. If you experience stomach distress, taking it with food or milk may help. 
  • Full course:It is critical to complete the entire prescribed course, even if symptoms vanish, to avoid the formation of drug-resistant germs. 

Important Safety Information about Septra DS

  • Allergies:Tell your doctor if you’ve ever been allergic to antibiotics before.
  • Discuss your medical history, particularly any liver or kidney illness, blood issues, or specific metabolic diseases. 
  • Drug Interaction:Some medicines may interact with Septra DS. Inform your healthcare practitioner about all of your drugs, including prescription, over-the-counter, vitamins, and herbal supplements. 

Fact Table for Septra DS

Generic Name Sulfamethoxazole/Trimethoprim

 

Brand Name(s)

 

Septra, Septra DS, Bactrim, Bactrim DS
Drug Class Antibiotic, specifically a combination of a sulfonamide antibiotic and a dihydrofolate reductase inhibitor

 

FDA Approval

 

Yes (specific date varies by country and formulation).

 

Indications Urinary tract infections, bronchitis, otitis media, shigellosis, pneumonia, traveler’s diarrhea, and certain types of infections in people with weakened immune systems.

 

Dosage Forms

 

Tablet, Oral Suspension
Adult Dosage
Typically, one Septra DS tablet every 12 hours for 10 to 14 days, depending on the infection and severity (dosage may vary by condition)
Pediatric Dosage

 

Dosage is based on weight and the type of infection (consult with a pediatrician).

 

Administration Oral, with or without food. If stomach upset occurs, taking with food or milk may help.

 

Common Side Effects Nausea, vomiting, loss of appetite, mild rash.

 

Serious Side Effects Severe skin reactions, blood disorders, liver or kidney issues, severe allergic reactions
Precautions Avoid if allergic to sulfa drugs or trimethoprim; caution in patients with liver or kidney disease, folate deficiency, or certain blood disorders.

 

Drug Interactions Warfarin, phenytoin, methotrexate, digoxin, and certain diuretics, among others.

 

Pregnancy Category Category D (evidence of human risk, but potential benefits may warrant use in pregnant women despite risks).

 

Breastfeeding Excreted in breast milk; consult a healthcare provider.

 

Mechanism of Action

 

Inhibits bacterial synthesis of dihydrofolic acid and tetrahydrofolic acid, essential components in bacterial DNA replication.

 

Common Side Effects of Septra DS

Like all medications, Septra DS (Sulfamethoxazole/Trimethoprim) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Nausea
  • Vomiting
  • Loss of appetite
  • Mild rash

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Septra DS (Sulfamethoxazole/Trimethoprim)?

You can order Septra DS (Sulfamethoxazole/Trimethoprim) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

Frequently Asked Questions

  1. Is Septra effective for viral infections?

    No, Septra fights bacteria, not viruses. Using it for viral infections like the flu won’t help and can contribute to antibiotic resistance, making bacteria stronger and harder to defeat. Save Septra for the battles it’s designed to fight!

  2. What about interactions with other medications?

    Septra can interact with many medications, altering their effectiveness or increasing side effects. Always inform your healthcare provider about all the potions (medications) you’re taking to avoid unintended interactions. Think of it as making sure all members of your team are working together harmoniously.

  3. Can Septra cause side effects?

    Yes, like any powerful ally, Septra can have side effects ranging from mild to severe. Common ones include nausea and skin rashes, but more serious reactions like allergic symptoms, severe skin reactions, or liver issues can occur. If you notice anything unusual, reach out to your healthcare professional – your sidekick in health – right away.

  4. What should I avoid while taking Septra?

    Antibiotics can make you sunburn more easily, so avoid the sun or cover up. Also, if you encounter diarrhea, don’t rush to anti-diarrhea medication without consulting your doctor first. Imagine you’re avoiding the villains’ traps while on your quest to better health.

  5. How should I take Septra?

    Follow your doctor’s instructions to the letter. Drink plenty of fluids to prevent kidney stones, and don’t cut your treatment short even if you start feeling better. Stopping too early can lead to resistance, making bacteria harder to defeat in the future. Think of it as completing a full course in hero training to ensure you’re ready for any battle.

  6. Can everyone use Septra?

    No, Septra isn’t suitable for everyone. It’s off-limits if you have severe liver or kidney disease, anemia caused by folic acid deficiency, or if you’re allergic to its components. Also, steer clear if you’re pregnant, breastfeeding, or if your medical history includes low platelets due to trimethoprim or sulfa drugs. Remember, even superheroes have their kryptonite!

  7. What is Septra?

    Septra is a combination antibiotic containing sulfamethoxazole and trimethoprim, targeting various bacterial infections. It’s particularly effective against ear infections, urinary tract infections, bronchitis, traveler’s diarrhea, and certain types of pneumonia. Despite its potency, it’s essential to use Septra responsibly to combat the bacteria it’s designed to fight.

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References
Septra ds [package insert].Bristol, TN: King Pharmaceuticals; 2006

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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