Resotran (Prucalopride)

Resotran
Prucalopride

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Prucalopride
Prucalopride Succinate

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Resotran (Prucalopride)

Resotran (Prucalopride) is a prescription medication designed to help treat chronic constipation. It works by stimulating bowel movement through its action on serotonin (5-HT4) receptors, helping to restore regular bowel function when lifestyle changes or other treatments have not been effective.

Why Choose Resotran (Prucalopride)?

  • Helps improve bowel movement in individuals with chronic constipation.
  • Stimulates natural bowel contractions for more regular and effective movements.
  • Typically works within 24 to 48 hours of use.
  • Suitable for long-term use, as recommended by healthcare professionals.
  • Clinically proven to enhance the quality of life for people struggling with constipation.

How to Use Resotran (Prucalopride)?

  • Follow Your Doctor’s Instructions: Take Resotran exactly as prescribed, usually once a day with or without food.
  • Take at the Same Time Daily: Consistency helps maintain regularity and maximizes effectiveness.
  • Swallow Whole: Do not crush or chew the tablet.
  • Stay Hydrated: Drink plenty of fluids throughout the day to support healthy digestion.
  • Monitor Your Symptoms: Keep track of any changes in your bowel movements and report to your doctor as needed.

Important Safety Information about Resotran

  • Not Suitable for Everyone: Consult your doctor if you have a history of intestinal obstruction, Crohn’s disease, or other serious gastrointestinal conditions.
  • Avoid Use During Pregnancy or Breastfeeding unless advised by your healthcare provider.
  • Inform Your Doctor of Other Medications: Resotran may interact with certain medications, including antidepressants or antibiotics.
  • Do Not Exceed the Recommended Dosage: Only take the prescribed amount to avoid complications.

Fact Table

 

Facts Details
Brand Name Resotran
Generic Name Prucalopride
Drug Class Serotonin 5-HT4 receptor agonist
Indication Treatment of chronic constipation when other treatments are ineffective
Mechanism of Action Stimulates serotonin receptors in the gut to promote bowel movement
Available Strengths 1 mg, 2 mg
Recommended Dosage 2 mg once daily, can be reduced to 1 mg based on patient tolerability
Time to Effect Typically 24–48 hours
Duration of Treatment Long-term use as prescribed by a healthcare provider
Who Can Use It? Adults (18+ years)
Who Should Avoid It? Patients with intestinal blockage, severe inflammatory bowel disease, or those with known hypersensitivity to the drug
How to Take Take orally once a day, with or without food
Common Side Effects Headache, nausea, diarrhea, abdominal pain, dizziness
Drug Interactions May interact with antidepressants, anticholinergic drugs, and antibiotics
Storage Instructions Store at room temperature (15-30°C); keep away from moisture and direct sunlight
Precautions Not recommended for people with severe kidney impairment without dosage adjustment

Common Side Effects

Like all medications, Resotran (Prucalopride) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Headache
  • Abdominal pain
  • Nausea
  • Diarrhea
  • Dizziness

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Resotran (Prucalopride)?

You can order Resotran (Prucalopride) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

Frequently Added Questions

  1. Can I discontinue using Resotran if I feel better?

    Do not discontinue using Resotran unless your doctor asks you to do so. Your symptoms of constipation may come back again if you stop using Resotran without consulting your doctor.

  2. List the ingredients of Resotran.

    Prucalopride is present as an active ingredient in Resotran. Magnesium stearate, lactose monohydrate, microcrystalline cellulose, and colloidal silicon dioxide are present as inactive ingredients in this medication.

    Titanium dioxide, polyethylene glycol 3000, hypromellose, triacetin, and lactose monohydrate are used to make its coating. Yellow iron oxide, FD&C Blue #2, and red iron oxide is present in its 2 mg tablet.

  3. Can I share Resotran with other patients who have the same symptoms?

    No, you should not share it with others even if they have the same symptoms. Doing this can be harmful to them.

  4. What if I miss a dose of Resotran?

    If you miss a dose, take it when you recall. If it is close to your next dose, skip the missed one and continue with your next dose. Don’t take an extra dose to make up for the missed dose.

  5. What if I overdose on Resotran?

    Contact your doctor right away if you overdose on Resotran.

  6. How to store Resotran?

    You should store Resotran at room temperature (20°C to 25°C) in its original container to prevent it from moisture. Make sure to keep this medicine inaccessible to children.

  7. What are the side effects of Resotran?

    Serious Side Effects:

    • Frequent behavior or mood changes
    • Self-harming or suicidal thoughts
    • Depression

    Consult your doctor if you experience these symptoms. If these symptoms get worse, stop using Resotran.
    Common Side Effects

    • Diarrhea
    • Nausea
    • Vomiting
    • Dizziness
    • Abdominal pain
    • Headache
    • Fatigue

    This list does not include all the side effects of Resotran. If you experience any side effects, immediately contact your healthcare provider.

  8. How many Resotran tablets should I take in a day?

    Usually, one tablet each day is recommended. But you should always ask your doctor, they can advise you better considering your health conditions.

  9. Do I need to take Resotran with food?

    There are no such food-related restrictions. You can take it with food or it can also be taken without food.

  10. What should I tell my healthcare provider before starting Resotran?

    Tell your healthcare provider about your medical conditions including the following conditions before starting Resotran:

    • Depression, self-harming thoughts, or frequent mood changes
    • Kidney problems
    • Pregnancy and breastfeeding

    Also, provide your healthcare provider with a list of all medications, vitamins, or supplements that you are currently using.

  11. Can children use Resotran?

    It is not confirmed whether Resotran is safe for children.

  12. Who should avoid Resotran?

    You should avoid Resotran if:

    • You are allergic to any ingredient present in Resotran. Allergic reaction symptoms are:
    • Itching and rashes
    • Swelling of face, throat, tongue, or lips.
    • Difficulty in breathing
    • You have a bowel blockage, a tear in your stomach or intestinal wall (bowel perforation), and severe intestinal wall problems like Crohn’s disease or ulcerative colitis.
  13. What is Resotran?

    Resotran is prescribed to manage idiopathic constipation (CIC) in adults. In such type of constipation, its cause is unknown.

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References
Prucalopride [package insert]. Lexington, MA: Shire US Inc; 2018.

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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