Humulin N Vial (Human Insulin)

Product Review

Humulin N Cartridge
Insulin Isophane (Nph)

Humulin N Vial
Insulin Isophane (Nph)

Humulin R Cartridge
Insulin Isophane (Nph)


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This is a refrigerated product.  A default $29.99 Express shipping fee is applied.  It will be shipped out in a insulated styrofoam container with gel and ice packs inside.  Parcels are shipped via Canada Post Express.

Humulin N Vials Drug Info (Pack with 1 Vial x 10 mL)


    Humulin N vials are filled with Humulin-N, which is the scientific name of insulin isophane, otherwise known as NPH insulin, which is used to control blood sugar levels in people with diabetes. It has been produced through human discovery, and is different from animal source insulin because it is structurally identical to the naturally occurring human insulin produced by your body. It is an intermediate-acting insulin with a slower onset of action than Regular insulin and a longer duration of activity. Humulin-N is a sterile solution containing insulin isophane for injection. It is available in 10 mL vials.


    Humulin N is the scientific name for insulin isophane, or NPH insulin. This type of insulin is an intermediate-acting insulin, which is sometimes called basal, or otherwise known as background insulin, because it provides a long duration of insulin protection against your blood sugar level fluctuations throughout the entire day. After injection once or twice a day it typically begins to work in 90 minutes and lasts for approximately 24 hours. Humulin-N is structurally identical to naturally occurring human insulin, but it contains blended small proteins called protamines to help slow down the onset and increase the duration of insulin action.


    Always follow the health advice of your doctor or other healthcare professional.

    If you are a new patient receiving insulin for the first time you can be started on Humulin N in the same way as you would be on animal source insulin. You should be monitored closely during this adjustment period.

    If switching from animal-source insulin to Humulin-N, it is possible that you will require a modification in dosage; the adjustment may be made with the first dose or over a period of several weeks.


    • Hypoglycemia (low blood sugar)

    • Breathing Problems

    • Dry Mouth

    • Itching

    • Stomach Pain

Frequently Asked Questions

  1. References

    Humulin N [Package Insert]. Indianapolis, IN: Eli Lilly and Company; 2018

  2. What are the necessary steps for preparing Humulin N for injection?

    Before using your Humulin N insulin, you need to make sure it’s ready for injection. Each time you use it, use a new needle. To mix the medication properly and make sure it’s evenly distributed in the vial, follow these steps:

    • Hold the vial in your hands and gently roll it between your palms about ten times. This helps mix the medication and gets rid of any settling that might have happened.
    • Turn the vial upside down about ten times as well. This further mixes the medication. But don’t shake the vial too hard.
    • Your Humulin N insulin is ready for injection when it looks cloudy and white, without any visible particles or lumps.

    Remember, always use a new needle each time you use your insulin for safety and effectiveness.

  3. Who should avoid Humulin N?

    Before you start using Humulin N insulin, talk to your doctor about your health history and the medicines you’re taking. People with other health problems or those taking different diabetes medicines like Actos or Avandia may need to change their Humulin N dose or try a different insulin. If you have kidney issues, liver issues, or heart problems, using Humulin N might be riskier for you. It’s important to discuss all of this with your doctor before using it.

  4. Can children be prescribed Humulin N?

    Yes, Humulin N has been tested and found to be safe and helpful for managing both type 1 and type 2 diabetes in children.

  5. Is Humulin N recommended for gestational diabetes?

    Yes. Humulin N can be a good choice for pregnant women who have gestational diabetes. If you have gestational diabetes when you’re pregnant, it’s important to talk to your doctor about using Humulin N to help control your blood sugar levels.

  6. Is Humulin N a fast-acting or long-acting insulin?

    Humulin N insulin, also known as isophane insulin human, is an intermediate-acting insulin. When people use Humulin N, it doesn’t work immediately; instead, it gradually enters the body and helps control blood sugar levels for about 12 to 18 hours after they inject it. This helps people with diabetes manage their blood sugar better.

  7. Is there any impact on Humulin N if it’s left out overnight?

    If you accidentally leave your Humulin N insulin out of the fridge overnight, it’s usually okay. It should still work fine and won’t be harmful. But if it gets hot or frozen, it might not work as well. If that happens, talk to your pharmacist or doctor because your insulin might not be good anymore.

  8. Is it safe to use cold Humulin N for my injection?

    Yes, it’s safe to use Humulin N that has been kept in the refrigerator. But, injecting cold insulin can hurt and be uncomfortable. So, it’s better to let it warm up to room temperature before using it.

  9. How long can I use a single vial of Humulin N?

    You can keep a vial of Humulin N in the fridge for 31 days. After 31 days, even if there’s still some left in the vial, you should throw it away.
    How many Humulin N vials are typically prescribed per month?
    Most people with diabetes usually need around two to three vials of Humulin N insulin every month. However, some people might need more vials depending on their specific needs.

  10. What if I miss a dose of Humulin N?

    If you forget to take your Humulin N medicine, talk to your pharmacist or the doctor who prescribed it to you. They might tell you to take the missed dose if your next dose is far away. But if your next dose is coming up soon, they might say it’s okay to skip the missed dose and take your next one at the usual time.

  11. What are the recommended injection sites for Humulin N?

    You should put the Humulin N under your skin’s fatty part. It’s best to use the backs of your upper arms, your belly, or the top and outer parts of your thighs as places to inject it. Remember to change where you inject it each time to keep your skin healthy and avoid problems like lumps or irritation. Also, make sure to use a new needle every time to stay safe and avoid infections.

  12. How can I modify my Humulin N dosage if necessary?

    If you want to modify Humulin N dosage, talk to your doctor first. Don’t make the change by yourself. Changing your Humulin N dose without your doctor’s advice can be dangerous. Your doctor can help you adjust your dose if needed. They might need to change it because of things like weight changes, diet changes, exercise changes, other medicines you’re taking, or if you have problems with your liver or kidneys.

  13. Can people with type 2 diabetes use Humulin N?

    Humulin N can be prescribed for both type 1 and type 2 diabetes patients. However, the recommended dosage for these two conditions usually differs, and individuals using Humulin N for these distinct conditions may have varying treatment outcomes.

  14. How do I calculate the right amount of Humulin N to take?

    To know how much Humulin N to use, you should talk to your doctor. They will help you decide the right amount. Usually, you start with a small dose and then adjust it as you learn how it affects your blood sugar. Other things that matter are your health, how much you exercise, and what you eat. Your doctor will consider all of these things to help you find the right dose of Humulin N.

  15. How many milliliters does a vial of Humulin N contain?

    Humulin N comes in two sizes: a small vial with 3 milliliters (mL) and a bigger one with 10 mL. They both have the same strength of insulin, which means there are 100 units of insulin in every 1 mL of liquid.

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Humulin N [Package Insert]. Indianapolis, IN: Eli Lilly and Company; 2018

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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