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Erleada (Apalutamide)
Erleada (Apalutamide)
Erleada (Apalutamide) belongs to a class of drugs known as androgen receptor inhibitors, which work by blocking the effects of androgen hormones that can promote tumor growth in the prostate gland. Erleada is typically used in patients with non-metastatic castration-resistant prostate cancer and other forms of advanced prostate cancer.
Why Choose Erleada (Apalutamide)?
- Reduces Risk of Metastasis: Significantly lowers the risk of prostate cancer spreading to other parts of the body.
- Extended Survival: This has been shown to prolong overall survival rates in patients with castration-resistant prostate cancer.
- Targeted Therapy: Specifically targets androgen receptors, making it a focused approach to inhibiting cancer cell growth.
- Oral Administration: Convenient oral tablet form, allowing for at-home treatment without the need for intravenous administration.
How to Use Erleada (Apalutamide)?
- Consultation and Prescription: Begin with a healthcare provider who can prescribe Erleada.
- Dosage Compliance: Take the prescribed dose, typically one tablet per day, around the same time each day.
- Continuous Monitoring: Regularly visit your healthcare provider for blood tests and monitoring of your health condition.
- Storage: Store the medication in a cool, dry place away from direct sunlight.
Important Safety Information about Erleada
- Medical History: Inform your doctor of your medical history, including any liver problems, heart conditions, or other serious health issues.
- Medication Interactions: Disclose all current medications, as Erleada can interact with other drugs, possibly altering effectiveness or causing side effects.
- Pregnancy and Exposure: Women who are pregnant or may become pregnant should not handle the medication without protection, as it can harm the fetus.
- Immediate Side Effects: Report any sudden health changes or allergic reactions to your healthcare provider.
Fact Table
| Facts | Details |
| Generic Name | Apalutamide |
| Brand Name | Erleada |
| Drug Class | Androgen receptor inhibitor |
| FDA Approval | Initially approved in 2018 |
| Indications | Treatment of non-metastatic castration-resistant prostate cancer (nmCRPC) |
| Form | Oral tablets |
| Common Dosage | 240 mg daily (four 60 mg tablets) |
| Administration | Taken with or without food |
| Storage Requirements | Store at room temperature, away from moisture and heat |
| Primary Mechanism | Blocks the effect of androgens, reducing the growth of cancer cells |
| Effectiveness | Extends metastasis-free survival and overall survival in nmCRPC patients |
| Key Side Effects | Fatigue, rash, hypertension, joint pain, decreased appetite |
| Precautions | Avoid in patients with severe hepatic impairment; monitor for signs of fracture or fall |
| Interactions | May interact with other medications metabolized by CYP3A4 and CYP2C8 enzymes |
| Pregnancy Category | Category X – Not for use in pregnancy |
Common Side Effects
Like all medications, Erleada (Apalutamide) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Fatigue
- Rash
- Hypertension
- Joint Pain
- Decreased Appetite
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Erleada (Apalutamide)?
You can order Erleada (Apalutamide) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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