Ziagen (Abacavir)

Ziagen (Abacavir)

Ziagen (Abacavir) is a prescription antiretroviral used to manage HIV-1 infection in adults and children. It belongs to a class of medicines called nucleoside reverse transcriptase inhibitors (NRTIs), which work by blocking the virus from multiplying in the body. Ziagen is often used in combination with other HIV medicines as part of a complete treatment plan. When taken regularly, it helps reduce viral load, improve immune function, and lower the risk of HIV-related complications.

Why Choose Ziagen (Abacavir)?

• Helps reduce the amount of HIV in the blood (viral load).
• Supports immune system recovery and function.
• Lowers the risk of HIV transmission when used consistently with other medications.
• Available in tablet and oral solution forms for flexible dosing.
• Can be used as part of a once-daily regimen for convenience and adherence.

How to Use Ziagen (Abacavir)?

• Take Ziagen exactly as prescribed by your healthcare provider.
• Swallow the tablet whole with or without food; if using the oral solution, measure carefully using the provided dosing device.
• Do not skip doses or stop taking Ziagen without consulting your doctor, as this can lead to resistance or treatment failure.
• Store at room temperature and keep away from heat, moisture, and direct light.

Important Safety Information about Ziagen

• Do not restart Ziagen if you have ever had an allergic reaction to it.
• Inform your doctor about any liver disease, heart problems, or alcohol use before starting treatment.
• Continue to take all HIV medicines as prescribed to prevent resistance.
• Ziagen does not cure HIV or prevent transmission; continue to follow safe practices.

Fact Table

 

Facts	Details
Brand Name	Ziagen
Generic Name	Abacavir
Drug Class	Nucleoside Reverse Transcriptase Inhibitor (NRTI)
Dosage Forms	Oral Tablet; Oral Solution
Indication	Used in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and children.
Mechanism of Action	Abacavir is converted to carbovir triphosphate inside the body, which inhibits HIV reverse transcriptase, an enzyme the virus needs to replicate. This helps reduce viral load and improve immune function.
Administration	Taken orally, with or without food. Consistency in timing each day is recommended.
Contraindications	– Known hypersensitivity to Abacavir or any component of the formulation. – HLA-B*5701–positive patients (due to risk of severe hypersensitivity reaction).
Common Side Effects	– Nausea, vomiting, diarrhea – Headache – Fatigue – Rash – Fever or malaise
Drug Interactions	– Alcohol increases abacavir plasma levels. – Avoid concurrent use with other abacavir-containing medications (e.g., Epzicom, Triumeq).
Monitoring Parameters	– Screen for HLA-B*5701 allele before starting. – Monitor liver function, viral load, and CD4 count periodically.
Use in Pregnancy	Classified as Pregnancy Category C. Should be used only if benefits outweigh risks. Often included in combination therapy for pregnant women with HIV.
Lactation	Not recommended; HIV-infected mothers should not breastfeed to avoid postnatal transmission.
Storage Conditions	Store at 25°C (77°F); excursions permitted to 15°–30°C (59°–86°F). Protect from moisture.

Common Side Effects

Like all medications, Ziagen (Abacavir) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Nausea, vomiting, or diarrhea
• Headache or fatigue
• Fever or chills
• Trouble sleeping
• Loss of appetite

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Ziagen (Abacavir)?

You can order Ziagen (Abacavir) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.