Vetoryl (Trilostane)
Vetoryl (Trilostane)
Vetoryl (Trilostane) is a prescription treatment for managing hyperadrenocorticism (Cushing’s disease) in dogs. It works by blocking the production of excess cortisol, helping to reduce symptoms such as increased thirst, frequent urination, hair loss, and lethargy. Vetoryl is the only veterinary-approved medication of its kind and is widely used to improve the quality of life in affected pets.
Why Choose Vetoryl (Trilostane)?
- Helps control symptoms of Cushing’s disease in dogs.
- Reduces excessive cortisol production.
- Improves energy levels, coat condition, and overall comfort.
- Veterinary-approved for safety and effectiveness.
- Available in multiple capsule strengths for precise dosing.
How to Use Vetoryl (Trilostane)?
- Administer once daily with food, or as directed by your veterinarian.
- Use the prescribed dose based on your dog’s weight and health condition.
- Do not break or open capsules; give whole.
- Monitor your dog’s progress through regular veterinary checkups and blood tests.
- Store at room temperature, away from moisture and heat.
Important Safety Information about Vetoryl
- For use in dogs only; not for cats or humans.
- Do not use in pregnant dogs or dogs with kidney or liver disease.
- Not recommended for dogs allergic to Trilostane or similar medications.
- Regular blood work is essential to adjust dosage and monitor adrenal function.
- Keep out of reach of children and other animals.
Fact Table
| Facts | Details |
| Brand Name | Vetoryl |
| Generic Name | Trilostane |
| Dosage Forms | Oral capsules |
| Indication | Treatment of hyperadrenocorticism (Cushing’s disease) in dogs caused by either pituitary-dependent or adrenal-dependent disease |
| Mechanism of Action | Inhibits the enzyme 3β-hydroxysteroid dehydrogenase, which blocks the production of cortisol and other adrenal steroids |
| Administration Route | Oral |
| Dosing Frequency | Once daily with food (or as directed by a veterinarian; in some cases may be given twice daily) |
| Prescription Status | Prescription-only |
| Onset of Effect | Clinical improvement often seen within 1–2 weeks; full effect monitored via follow-up blood tests |
| Duration of Treatment | Long-term or lifelong in most cases, depending on the underlying condition |
| Storage Conditions | Store at 68°F–77°F (20°C–25°C); protect from moisture and light |
| Key Benefits | Reduces excessive cortisol levels; improves energy, appetite regulation, coat quality, and overall quality of life |
| Contraindications | Dogs with hypersensitivity to Trilostane, pregnant dogs, dogs with primary hepatic or renal disease, or dogs with adrenal gland disorders unrelated to Cushing’s |
| Warnings & Precautions | Requires regular blood monitoring; dosage adjustments may be needed; discontinue if signs of hypoadrenocorticism occur |
| Common Side Effects | Lethargy, reduced appetite, vomiting, diarrhea, weakness |
| Overdose Risk | May lead to acute adrenal insufficiency; emergency veterinary treatment required |
Common Side Effects
Like all medications, Vetoryl (Trilostane) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Reduced appetite
- Vomiting or diarrhea
- Lethargy or decreased energy
- Weakness
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Vetoryl (Trilostane)?
You can order Vetoryl (Trilostane) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
