Tylenol Cold Extra Strength Day + Night (Combo Pack)

Tylenol Cold Extra Strength Day + Night (Combo Pack)

Tylenol Cold Extra Strength Day + Night Combo Pack provides powerful relief from cold and flu symptoms, tailored for around-the-clock comfort. The Daytime formula helps you stay alert and productive while relieving congestion, sore throat, and headaches. The Nighttime formula soothes your body so you can rest more easily by easing cough, runny nose, and sinus pressure. Together, they work to help you recover faster and feel better day and night.

Why Choose Tylenol Cold Extra Strength Day + Night (Combo Pack)?

• Daytime relief: Reduces fever, clears nasal congestion, and eases body aches without drowsiness.
• Nighttime relief: Relieves cough, runny nose, and sinus pain to promote restful sleep.
• Fast-acting formula: Starts working quickly to provide comfort when you need it most.
• All-day care: Combines two targeted formulas for full 24-hour symptom management.

How to Use Tylenol Cold Extra Strength Day + Night (Combo Pack)?

• Read the label carefully before use and follow dosage instructions exactly.
• For adults and children 12 years and older: Take 2 caplets of Daytime every 4 hours as needed (maximum 8 caplets in 24 hours). Take 2 caplets of Nighttime at bedtime only (maximum 2 caplets in 24 hours).
• Do not exceed the recommended dose or combine with other acetaminophen-containing products.
• Store in a cool, dry place, away from children’s reach.

Important Safety Information about Tylenol Cold Extra Strength

• Do not use if you are taking or have taken MAO inhibitors within the past 2 weeks.
• Avoid alcohol while using this product, as it increases the risk of liver damage.
• Consult your doctor if you have high blood pressure, liver disease, thyroid disorder, or a persistent cough.
• Stop use and seek medical help if symptoms last more than 7 days, worsen, or are accompanied by a fever that persists.
• Pregnant or breastfeeding women should consult a healthcare professional before use.

Fact Table

 

Facts	Details
Brand Name	Tylenol Cold Extra Strength Day + Night Combo Pack
Generic Name	Acetaminophen / Dextromethorphan HBr / Phenylephrine HCl / Diphenhydramine HCl
Product Type	Over-the-counter (OTC) cold and flu relief combination
Dosage Form	Caplets (Day and Night formulations)
Pack Contents	Daytime Caplets + Nighttime Caplets (Combo Pack)
Purpose	Temporary relief of symptoms associated with cold, flu, and sinus congestion
Active Ingredients (Day Caplets)	– Acetaminophen 500 mg – Pain reliever/fever reducer – Dextromethorphan HBr 10 mg – Cough suppressant – Phenylephrine HCl 5 mg – Nasal decongestant
Active Ingredients (Night Caplets)	– Acetaminophen 500 mg – Pain reliever/fever reducer – Dextromethorphan HBr 10 mg – Cough suppressant – Phenylephrine HCl 5 mg – Nasal decongestant – Diphenhydramine HCl 25 mg – Antihistamine (relieves runny nose and promotes rest)
Inactive Ingredients	Cellulose, corn starch, croscarmellose sodium, magnesium stearate, povidone, sodium starch glycolate, stearic acid, and color additives.
Indications / Uses	– Headache, minor aches, and pains – Sore throat pain – Nasal congestion and sinus pressure – Cough suppression – Runny nose and sneezing (nighttime) – Fever reduction
Contraindications	– Severe liver disease or active liver failure – Use with other products containing acetaminophen or MAO inhibitors – Allergy to any component of the product
Warnings	– Liver Warning: Contains acetaminophen. Severe liver damage may occur if you take more than 4000 mg in 24 hours. – Alcohol Warning: Avoid alcoholic beverages while taking this product. – Do Not Use: With other cold, cough, or sleep medications unless directed by a doctor. – Ask a Doctor Before Use If You Have: Heart disease, high blood pressure, thyroid disease, diabetes, glaucoma, or breathing problems.
Side Effects (Possible)	– Drowsiness (especially nighttime formula) – Dizziness or nervousness – Upset stomach or nausea – Dry mouth or throat – Allergic reaction (rare)
Storage Instructions	Store at 15–30°C (59–86°F). Keep tightly closed and away from moisture.
Availability	Available over the counter in most pharmacies and online stores.

Common Side Effects

Like all medications, Tylenol Cold Extra Strength Day + Night (Combo Pack) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Drowsiness (with the Nighttime formula)
• Dry mouth or mild dizziness
• Upset stomach or nausea

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Tylenol Cold Extra Strength Day + Night (Combo Pack)?

You can order Tylenol Cold Extra Strength Day + Night (Combo Pack) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.