Tremfya (Guselkumab)

Tremfya (Guselkumab)

Tremfya (guselkumab) is a prescription medication used for the treatment of moderate to severe plaque psoriasis in adults who may benefit from systemic therapy or phototherapy, and adult patients with active psoriatic arthritis. As a selective IL-23 inhibitor, Tremfya targets specific proteins that are associated with inflammatory processes of the disease, helping to reduce symptoms and manage the conditions effectively.

Why Choose Tremfya (Guselkumab)?

• Targeted Treatment: Tremfya specifically targets the IL-23 protein, a key driver of inflammatory processes in psoriasis, providing focused and effective treatment.
• Improves Skin Clearance: Clinically proven to help achieve clearer skin in many patients with plaque psoriasis.
• Long-lasting Effects: Offers sustained symptom control with appropriate usage, which can improve the quality of life.
• Convenient Dosing: Administered as an injection once every 8 weeks after initial starter doses, allowing for less frequent dosing compared to some other therapies.

How to Use Tremfya (Guselkumab)?

• Initial Dosing: Tremfya is administered as a subcutaneous injection. The recommended initial dose is given at week 0, followed by a second dose at week 4.
• Maintenance Dosing: After the initial doses, Tremfya is typically given once every 8 weeks.
• Administration: Always use Tremfya exactly as your healthcare provider has instructed. The injection can be done at home by the patient or a caregiver, following training by a healthcare professional.
• Storage and Handling: Store in a refrigerator, protect from light, and do not freeze. Allow the medication to reach room temperature before injecting.

Important Safety Information about Tremfya

• Infections: Tremfya may increase the risk of infections. Tell your doctor if you have signs of an infection, such as fever, sweats, or chills.
• Allergic Reactions: If you experience any symptoms of a serious allergic reaction such as hives, difficulty breathing, or swelling of your face, lips, tongue, or throat, seek medical attention immediately.
• Vaccinations: Avoid using live vaccines while taking Tremfya. Discuss your vaccination history with your healthcare provider.

Fact Table

 

Facts	Details
Generic Name	Guselkumab
Brand Name	Tremfya
FDA Approval	Approved in 2017 for plaque psoriasis; later approved for psoriatic arthritis.
Drug Type	Monoclonal antibody
Mechanism of Action	Inhibits the interleukin-23 (IL-23) protein which is involved in inflammation.
Indications	Moderate to severe plaque psoriasis, active psoriatic arthritis in adults.
Administration	Subcutaneous injection
Dosage Form	Pre-filled syringe
Initial Dosing	100 mg at week 0, followed by 100 mg at week 4
Maintenance Dosing	100 mg every 8 weeks
Common Side Effects	Upper respiratory infections, headaches, injection site reactions, joint pain, diarrhea, fungal skin infections
Special Considerations	Screen for TB before treatment; monitor for signs of infection; avoid live vaccines during treatment
Storage Requirements	Store in refrigerator, protect from light, do not freeze

 

Common Side Effects

Like all medications, Tremfya (Guselkumab) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Upper respiratory infections
• Headaches
• Injection site reactions
• Joint pain
• Diarrhea

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Tremfya (Guselkumab)?

You can order Tremfya (Guselkumab) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.