Purinethol (Mercaptopurine)

 

Purinethol (Mercaptopurine)

Purinethol, also known as Mercaptopurine, is a medication primarily used in the treatment of acute lymphoblastic leukemia (ALL). It belongs to a class of drugs known as purine analogs, which work by interfering with the growth of cancer cells, ultimately reducing their spread and aiding in the control of the disease.

Why Choose Purinethol (Mercaptopurine)?

• Effective in Leukemia Treatment: Proven to be effective in managing acute lymphoblastic leukemia and other related conditions.
• Integrates with Other Therapies: Can be used in combination with other chemotherapy treatments to enhance efficacy.
• Long Track Record: This has been used in medical practice for decades, providing a well-understood profile of its effectiveness and safety.

How to Use Purinethol (Mercaptopurine)?

• Dosage: Follow the prescribed dosage exactly. Do not alter the dose or the frequency without consulting your doctor. The dosage can vary widely depending on individual needs and blood test results.
• Administration: Purinethol is usually taken orally in the form of a tablet. It can be taken with or without food. However, taking it with food may help reduce stomach upset.
• Timing: Try to take the medication at the same time each day to maintain an even level of the medication in your blood.
• Duration of Treatment: Continue taking the medication as prescribed even if you feel well. Do not stop taking Purinethol without discussing it with your doctor, as abruptly stopping can worsen your condition.
• Handling Instructions: Handle the tablets with care. Avoid crushing or breaking them, and wash your hands before and after handling the medication.

Important Safety Information about Purinethol

• Not for Pregnancy: This can cause harm to an unborn baby; effective contraception is recommended for both males and females using this medication.
• Avoid Live Vaccines: Avoid vaccinations/immunizations with live vaccines while using this medication unless your doctor tells you otherwise.
• Drug Interactions: Can interact with various other medications; inform your healthcare provider about all other medicines you are taking.
• Storage: Store the medication at room temperature, away from moisture and heat. Keep it out of reach of children and pets.

Fact Table

 

Facts	Details
Generic Name	Mercaptopurine
Brand Names	Purinethol, Purixan
Drug Class	Antimetabolite, Purine analog
Indications	– Acute lymphoblastic leukemia (ALL) – Chronic myeloid leukemia (CML) – Used as part of chemotherapy regimens
How it Works	Inhibits DNA synthesis, thus stopping the growth of cancer cells.
Dosage Forms	– Oral tablet – Oral Suspension
Common Dosages	Dosing is highly individualized based on the type of leukemia, the patient’s weight, age, and overall health. Follow the oncologist’s prescription closely.
How to Take	Take on an empty stomach, at least 1 hour before or 2 hours after meals. Swallow tablets whole, do not crush or chew.
Storage	Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
Important Safety Information	– Regular blood tests are needed to monitor effects. – Use effective birth control to avoid pregnancy during treatment. – Not recommended for use in patients with a history of severe bone marrow suppression.
Common Side Effects	– Nausea and vomiting – Rash – Low blood cell counts leading to increased risk of infection, bleeding or bruising – Liver dysfunction
Interactions	– Allopurinol (increases toxicity) – Warfarin (affects blood clotting) – Certain vaccines (live vaccines can be dangerous during treatment)
Contraindications	– Known hypersensitivity to mercaptopurine or any component of the formulation – Severe bone marrow suppression before treatment starts

Common Side Effects

Like all medications, Purinethol (Mercaptopurine) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Nausea 
• Vomiting
• Rash
• Low blood cell counts

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Purinethol (Mercaptopurine)?

You can order Purinethol (Mercaptopurine) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.