Pentasa (Mesalamine)

Pentasa (Mesalamine)

Pentasa (Mesalamine) is an anti-inflammatory treatment designed to manage and relieve symptoms of mild to moderate ulcerative colitis and Crohn’s disease. It works directly in the colon to reduce inflammation, ease abdominal pain, and promote long-term intestinal healing. Pentasa helps patients achieve remission and maintain a better quality of life by controlling flare-ups and supporting gut health.

Why Choose Pentasa (Mesalamine)?

• Helps reduce inflammation in the colon and intestines
• Supports remission in ulcerative colitis and Crohn’s disease
• Relieves symptoms such as diarrhea, rectal bleeding, and stomach pain
• Acts locally in the digestive tract for targeted relief
• Available in oral and rectal formulations for flexible treatment options

How to Use Pentasa (Mesalamine)?

• Take Pentasa exactly as prescribed by your healthcare provider
• Swallow capsules or tablets whole; do not crush or chew
• Take with or without food, preferably at the same time daily
• Drink plenty of fluids throughout the day
• Continue using the medication even if symptoms improve unless advised otherwise
• Store at room temperature and keep away from moisture and direct heat

Important Safety Information about Pentasa

• Inform your doctor if you have kidney, liver, or heart problems before starting Pentasa
• Regular blood and urine tests may be required to monitor kidney function
• Avoid taking Pentasa if allergic to mesalamine, aspirin, or salicylates
• Report symptoms like chest pain, shortness of breath, or severe stomach pain immediately
• Not recommended for use during pregnancy or breastfeeding without medical supervision

Fact Table

 

Facts	Details
Brand Name	Pentasa
Generic Name	Mesalamine
Drug Class	5-Aminosalicylic Acid (5-ASA); Anti-inflammatory agent
Dosage Forms	Oral tablets, extended-release capsules, rectal suppositories, rectal enemas
Active Ingredient	Mesalamine
Mechanism of Action	Mesalamine acts locally in the colon to reduce inflammation by inhibiting the production of inflammatory chemicals like prostaglandins and leukotrienes.
Indications / Uses	Treatment and maintenance of remission in mild to moderate ulcerative colitis and Crohn’s disease.
Onset of Action	May take several weeks to achieve noticeable improvement.
Route of Administration	Oral or rectal, depending on the formulation.
How to Take	Swallow tablets/capsules whole with water. Do not crush or chew. Rectal forms should be used as directed (usually at bedtime).
Storage Conditions	Store at room temperature (20°C–25°C / 68°F–77°F). Protect from moisture and direct sunlight.
Precautions	Use with caution in patients with kidney or liver disease. Regular monitoring of renal function is advised.
Contraindications	Known hypersensitivity to mesalamine, salicylates, or any component of the formulation.
Drug Interactions	May interact with azathioprine, 6-mercaptopurine, and nephrotoxic drugs (can increase risk of kidney damage).
Common Side Effects	Headache, nausea, abdominal pain, flatulence, diarrhea, dizziness, rash.
Monitoring Parameters	Kidney function (serum creatinine, BUN), liver function tests, complete blood count (CBC).

Common Side Effects

Like all medications, Pentasa (Mesalamine) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Headache or mild nausea
• Abdominal pain or cramps
• Diarrhea or gas
• Dizziness or fatigue
• Rash or itching

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Pentasa (Mesalamine)?

You can order Pentasa (Mesalamine) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.