Glyxambi (Empagliflozin / Linagliptin)

 

Glyxambi (Empagliflozin/ Linagliptin)

Glyxambi combines two medications, Empagliflozin and Linagliptin, in one convenient pill. It is used to help manage blood sugar levels in adults with type 2 diabetes, especially when diet and exercise alone aren’t enough. This medication works by helping the kidneys remove sugar through urine (Empagliflozin) and increasing insulin production while lowering blood sugar (Linagliptin). Glyxambi is not for type 1 diabetes or diabetic ketoacidosis.

Why Choose Glyxambi (Empagliflozin/ Linagliptin)?

• Helps control blood sugar levels in adults with type 2 diabetes.
• Combines two effective medications in one pill for convenience.
• Can help reduce the risk of cardiovascular complications in diabetic patients.
• Supports weight management by helping eliminate excess sugar.
• Taken once daily, making it easy to incorporate into your routine.

How to Use Glyxambi (Empagliflozin/ Linagliptin)?

• Take exactly as prescribed by your healthcare provider.
• It is typically taken once a day, with or without food.
• Drink plenty of water while on Glyxambi to avoid dehydration.
• Regularly check blood sugar levels as recommended by your doctor.
• Combine Glyxambi with a healthy diet and exercise for best results.
• Store in a cool, dry place, away from direct sunlight.

Important Safety Information about Glyxambi

• Not suitable for patients with type 1 diabetes or diabetic ketoacidosis.
• Avoid use if you have severe kidney disease or are on dialysis.
• Inform your doctor if you have a history of pancreatitis, urinary tract infections, or cardiovascular conditions.
• Dehydration, low blood pressure, or kidney issues may occur. Stay hydrated and consult your doctor if you experience dizziness or weakness.
• Do not use Glyxambi if pregnant, planning to become pregnant, or breastfeeding without consulting your doctor.

Fact Table

 

Facts	Details
Brand Name	Glyxambi
Generic Name	Empagliflozin / Linagliptin
Drug Class	SGLT2 Inhibitor (Empagliflozin) + DPP-4 Inhibitor (Linagliptin)
Indication	Type 2 Diabetes Mellitus (as an adjunct to diet and exercise to improve glycemic control)
Dosage Form	Oral tablet
Strengths Available	10 mg Empagliflozin / 5 mg Linagliptin, 25 mg Empagliflozin / 5 mg Linagliptin
Route of Administration	Oral
Recommended Dosage	Once daily, with or without food
Mechanism of Action	– Empagliflozin: Increases glucose excretion through the urine by inhibiting SGLT2 in the kidneys.- Linagliptin: Increases insulin release and decreases glucagon levels by inhibiting the DPP-4 enzyme.
Key Benefits	– Improves blood sugar control – Reduces cardiovascular risks – Convenient once-daily dosing
Who Should Avoid	– Type 1 diabetes – Diabetic ketoacidosis – Patients with severe renal impairment – Pregnant or breastfeeding women without medical advice
Common Side Effects	– Urinary tract infections – Nasal congestion – Increased urination – Joint pain – Hypoglycemia (when combined with other diabetes medications)
Drug Interactions	– Insulin and sulfonylureas (increased risk of hypoglycemia) – Diuretics (may increase dehydration risk) – ACE inhibitors, ARBs, NSAIDs (may affect kidney function)
Precautions	– Stay hydrated to avoid dehydration – Monitor kidney function regularly – Check for signs of hypoglycemia, especially if on insulin
Storage Instructions	Store at room temperature, away from moisture and heat. Keep out of reach of children.
FDA Approval	Yes (Approved in 2015)

Common Side Effects

Like all medications, Glyxambi (Empagliflozin/ Linagliptin) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Urinary tract infections
• Nasal congestion or sore throat
• Increased urination
• Diarrhea or stomach discomfort
• Joint pain

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Glyxambi (Empagliflozin/ Linagliptin)?

You can order Glyxambi (Empagliflozin/ Linagliptin) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.