Malarone (Atovaquone / Proguanil Hydrochloride)

Atovaquone/proguanil (Generic)

Atovaquone, Proguanil Hydrochloride

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Malarone (Atovaquone/ Proguanil Hydrochloride)

Malarone is a trusted antimalarial medication combining atovaquone and proguanil hydrochloride, designed to prevent and treat malaria. This medication works by targeting the Plasmodium parasites responsible for malaria, disrupting their growth and reproduction.

Why Choose Malarone (Atovaquone/ Proguanil Hydrochloride)?

  • Effective Malaria Protection: Proven to prevent and treat Plasmodium falciparum malaria, the most common and severe strain.
  • Convenient Dosage: A simple, once-daily tablet makes adherence to prevention or treatment easy.
  • Dual-Action Formula: Combines two active ingredients for a stronger, synergistic effect against malaria parasites.
  • Minimal Drug Interactions: Compatible with most common medications when taken as directed.
  • Well-tolerated: Low incidence of severe side effects compared to other antimalarial medications.

How to Use Malarone (Atovaquone/ Proguanil Hydrochloride)?

  • For Prevention: Begin taking Malarone 1-2 days before traveling to a malaria-endemic area. Continue daily dosing throughout your stay. Keep taking Malarone for 7 days after leaving the area.
  • For Treatment: Follow your healthcare provider’s instructions carefully regarding dosage and duration. Typically, it is taken daily for 3 consecutive days as prescribed. Take with Food or Milk: Enhances absorption and reduces the risk of stomach upset.
  • Adhere to Schedule: Take your tablet at the same time every day for consistency.
  • Avoid Missing Doses: Maintain protection by ensuring no skipped doses, particularly during exposure.

Important Safety Information about Malarone

  • Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
  • Share your complete medical history, including liver and kidney conditions.
  • Stay hydrated to reduce the risk of stomach upset.
  • Discuss any other medications, supplements, or herbal products you’re taking to avoid interactions.
  • Pay special attention to medications for blood thinning, seizures, or certain antibiotics.
  • Malaria medications may increase sensitivity to sunlight; use sunscreen and protective clothing.

Fact Table

 

Facts Details
Brand Name Malarone
Generic Name Atovaquone/Proguanil Hydrochloride
Medication Type Antimalarial
Purpose Prevention and treatment of malaria caused by Plasmodium falciparum
Active Ingredients – Atovaquone: 250 mg per tablet – Proguanil Hydrochloride: 100 mg per tablet
Dosage Form Oral tablet
How It Works Inhibits the parasite’s ability to grow and reproduce within the red blood cells.
Onset of Action Begins to act shortly after ingestion; full effect depends on adherence to the prescribed regimen.
Usage Instructions – Take with food or milk to improve absorption. – Maintain consistent daily timing for doses.
Target Parasites Effective against Plasmodium falciparum (including drug-resistant strains).
Who Can Use Adults and children weighing at least 11 pounds (5 kg).
Who Should Not Use – Individuals allergic to atovaquone or proguanil. – Patients with severe kidney impairment.
Common Side Effects Headache, nausea, diarrhea, stomach pain, mild skin rash.
Drug Interactions – Blood thinners (e.g., warfarin). – Rifampin and other antibiotics. – Antiseizure medications.
Precautions – Use sunscreen and protective clothing (may increase sun sensitivity). – Do not skip doses.
Storage Instructions Store at room temperature (68–77°F or 20–25°C). Keep out of reach of children.
Prescription Required Yes

Common Side Effects

Like all medications, Malarone (Atovaquone/ Proguanil Hydrochloride) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Headache
  • Nausea or vomiting
  • Stomach pain
  • Diarrhea
  • Mild skin rash

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Malarone (Atovaquone/ Proguanil Hydrochloride)?

You can order Malarone (Atovaquone/ Proguanil Hydrochloride) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

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