Lokelma (Sodium Zirconium Cyclosilicate)

 

Lokelma (Sodium Zirconium Cyclosilicate)

Lokelma (Sodium Zirconium Cyclosilicate) is a prescription treatment used to manage high levels of potassium in the blood (hyperkalemia). It works by trapping potassium in the digestive tract, allowing it to be removed from the body naturally. Lokelma is designed to act quickly, lowering potassium levels within hours, and can be used for both short-term correction and long-term management under medical supervision.

Why Choose Lokelma (Sodium Zirconium Cyclosilicate)?

• Helps restore normal potassium levels safely and effectively.
• Begins to work within 1-2 hours of ingestion.
• Can be used for ongoing management of hyperkalemia.
• Tasteless, odorless powder, easy to mix with water.
• Clinically proven to maintain stable potassium levels long term.

How to Use Lokelma (Sodium Zirconium Cyclosilicate)?

• Always take Lokelma exactly as prescribed by your healthcare provider.
• Mix the powder in water before consuming; never take it dry.
• Take it at the same time each day for consistent results.
• Separate Lokelma from other oral medications by at least 2 hours (before or after).
• Continue to follow your doctor’s dietary and medication guidance to control potassium levels.

Important Safety Information about Lokelma

• Do not use Lokelma if you have severe constipation, bowel obstruction, or impaction.
• Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant.
• Tell your healthcare provider about all other medications you take, as Lokelma may affect how other drugs are absorbed.
• Regular monitoring of potassium and sodium levels is recommended during treatment.
• Store at room temperature, away from moisture and direct sunlight.

Fact Table

 

Facts	Details
Brand Name	Lokelma
Generic Name	Sodium Zirconium Cyclosilicate
Drug Class	Potassium binder
Dosage Form	Oral powder for suspension
Prescription Status	Prescription only
Indication	Treatment of hyperkalemia (high potassium levels) in adults
Mechanism of Action	Lokelma is a non-absorbed, inorganic cation exchange compound. It selectively captures potassium ions in exchange for sodium and hydrogen ions throughout the gastrointestinal tract, lowering serum potassium levels.
Onset of Action	Typically, within 1 to 2 hours after ingestion
Duration of Effect	Sustained potassium reduction for up to 24 hours per dose
Administration Instructions	– Mix the contents of the packet in at least 45 mL of water and stir well before drinking. – Consume immediately after preparation. – Can be taken with or without food. – Do not heat or add to heated foods or liquids.
Contraindications	– Hypersensitivity to Sodium Zirconium Cyclosilicate or any component of the formulation.
Warnings & Precautions	– May cause edema due to sodium content; use caution in patients with heart failure, kidney disease, or on sodium-restricted diets. – Separate from other oral medications by at least 2 hours before or after to avoid absorption issues.
Common Side Effects	– Edema (fluid retention) – Mild constipation – Hypokalemia (low potassium, if overdosed) – Fatigue – Gastrointestinal discomfort
Drug Interactions	– Can affect absorption of oral drugs; separate dosing by at least 2 hours. – Caution with medications that increase sodium load (e.g., NSAIDs).
Storage Instructions	– Store at room temperature (15°C–30°C / 59°F–86°F). – Keep packets in their original packaging until use.
Overdose Management	– May result in hypokalemia; discontinue and monitor potassium levels. – Supportive therapy as needed.

Common Side Effects

Like all medications, Lokelma (Sodium Zirconium Cyclosilicate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Mild constipation
• Swelling in hands, ankles, or feet (edema)
• Nausea or upset stomach
• Low potassium levels (if overcorrected)
• Mild changes in blood pressure or sodium levels

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Lokelma (Sodium Zirconium Cyclosilicate)?

You can order Lokelma (Sodium Zirconium Cyclosilicate) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.