Gengraf (Cyclosporine Modified)

 

Gengraf (Cyclosporine Modified)

Gengraf (Cyclosporine Modified) is an immunosuppressant medication primarily used to prevent organ rejection in transplant patients. It works by suppressing the body’s immune response to help the body accept a new organ (such as a kidney, liver, or heart). It may also be prescribed for certain autoimmune conditions like rheumatoid arthritis and psoriasis.

Why Choose Gengraf (Cyclosporine Modified)?

• Prevents Organ Rejection: Helps transplanted organs function properly by reducing immune system activity.
• Effective for Autoimmune Disorders: Provides relief for severe rheumatoid arthritis and psoriasis when other treatments have failed.
• Consistent Absorption: The modified formulation ensures predictable absorption and steady therapeutic levels in the bloodstream.
• Convenient Dosage Forms: Available in capsules and oral solutions for flexible dosing options.

How to Use Gengraf (Cyclosporine Modified)?

• Take as Prescribed: Always follow your healthcare provider’s instructions regarding dosage and timing.
• Consistency is Key: Take Gengraf at the same time each day to maintain steady drug levels.
• With or Without Food: Be consistent in how you take it—either always with food or always on an empty stomach.
• Avoid Grapefruit Products: Grapefruit can interfere with how your body absorbs Gengraf.
• Monitor Blood Levels: Regular blood tests are crucial to ensure the correct drug concentration and prevent toxicity.
• Stay Hydrated: Drink plenty of water to support kidney health while on this medication.

Important Safety Information about Gengraf

• Infection Risk: Gengraf suppresses the immune system, increasing your risk of infections. Maintain proper hygiene and avoid contact with sick individuals.
• Liver and Kidney Function: This medication can affect liver and kidney function. Routine tests are necessary to monitor organ health.
• Blood Pressure and Cholesterol: Gengraf may cause high blood pressure and increased cholesterol levels, so regular monitoring is important.
• Drug Interactions: Inform your doctor of all medications, supplements, and herbal products you are taking, as Gengraf interacts with many drugs.
• Avoid Live Vaccines: Since your immune system is suppressed, avoid live vaccines during treatment.

Fact Table

 

Facts	Details
Generic Name	Cyclosporine Modified
Brand Name	Gengraf
Drug Class	Immunosuppressant
Primary Use	Prevention of organ transplant rejection (kidney, liver, heart) and treatment of rheumatoid arthritis and psoriasis.
Dosage Forms	Capsules (25 mg, 50 mg, 100 mg), Oral solution
Route of Administration	Oral
Mechanism of Action	Gengraf suppresses the immune system by inhibiting the activity of T-lymphocytes, a type of white blood cell involved in immune responses.
Key Benefits	– Reduces the risk of organ transplant rejection. – Effective in controlling symptoms of rheumatoid arthritis. – Helps manage severe psoriasis.
Onset of Action	1-2 hours (peak blood concentration)
Recommended Storage	– Store at room temperature (20°C to 25°C). – Protect from moisture and light.
How to Take	– Take consistently with or without food. – Avoid grapefruit and grapefruit juice as they may increase drug levels in the blood.
Missed Dose	If a dose is missed, take it as soon as you remember. If it’s close to the next dose, skip the missed dose. Do not double the dose to catch up.
Precautions	– Regular monitoring of blood pressure and kidney function is required. – Use with caution in patients with high blood pressure or kidney problems.
Common Side Effects	– High blood pressure – Headache – Nausea and vomiting – Increased hair growth (hirsutism) – Tremors – Kidney dysfunction
Drug Interactions	– Avoid with drugs like potassium-sparing diuretics, NSAIDs, and certain antibiotics. – Grapefruit juice increases the risk of toxicity.

Common Side Effects

Like all medications, Gengraf (Cyclosporine Modified) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• High blood pressure
• Increased hair growth (hirsutism)
• Swollen gums
• Tremors
• Nausea and vomiting
• Headache

If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Gengraf (Cyclosporine Modified)?

You can order Gengraf (Cyclosporine Modified) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.