Fetzima (Levomilnacipran)
Fetzima (Levomilnacipran)
Fetzima (Levomilnacipran) is an antidepressant medication belonging to the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is primarily prescribed for the treatment of major depressive disorder (MDD) in adults. By balancing serotonin and norepinephrine levels in the brain, Fetzima helps improve mood, energy levels, and overall daily functioning in individuals experiencing depression.
Why Choose Fetzima (Levomilnacipran)?
- Clinically proven to treat major depressive disorder (MDD) in adults.
- Helps improve mood, motivation, and energy levels.
- Supports better focus and daily functioning.
- Provides relief from persistent feelings of sadness, hopelessness, and fatigue.
- Once-daily capsule for convenient use.
How to Use Fetzima (Levomilnacipran)?
- Take exactly as prescribed by your healthcare provider.
- Fetzima is usually taken once daily, at the same time each day, with or without food.
- Swallow capsules whole; do not crush, chew, or split.
- Do not suddenly stop taking without medical guidance; tapering may be necessary.
- If you miss a dose, take it as soon as you remember, unless it is close to your next dose.
- Regular follow-ups with your healthcare provider are recommended to monitor progress and adjust dosage if needed.
Important Safety Information about Fetzima
- Not approved for use in children or adolescents under 18 years.
- May increase risk of suicidal thoughts or behaviors, especially in young adults.
- Inform your doctor if you have a history of heart problems, high blood pressure, glaucoma, or seizures.
- Avoid combining with MAO inhibitors, other antidepressants, or certain pain medications, as this may cause serious interactions.
- Alcohol use should be limited or avoided while taking Fetzima.
- Use caution when operating machinery or driving until you know how the medication affects you.
Fact Table
| Facts | Details |
| Brand Name | Fetzima |
| Generic Name | Levomilnacipran |
| Drug Class | Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) |
| Dosage Forms | Extended-release capsules |
| Route of Administration | Oral (by mouth) |
| Indication | Treatment of Major Depressive Disorder (MDD) in adults |
| Mechanism of Action | Inhibits reuptake of serotonin (5-HT) and norepinephrine (NE) in the brain, increasing availability of these neurotransmitters to help regulate mood. |
| Administration Notes | – Take once daily, at the same time each day. – May be taken with or without food. – Swallow capsule whole (do not crush, chew, or open). |
| Contraindications | – Hypersensitivity to levomilnacipran or any component – Use with or within 14 days of MAOIs (risk of serotonin syndrome) |
| Warnings & Precautions | – Increased risk of suicidal thoughts and behaviors in young adults and adolescents – Risk of serotonin syndrome when combined with other serotonergic drugs – May increase blood pressure and heart rate; monitor regularly – Can cause urinary hesitation/retention – Use cautiously in patients with renal impairment |
| Common Side Effects | – Nausea – Constipation – Increased sweating – Tachycardia – Palpitations – Dizziness – Insomnia – Erectile dysfunction / decreased libido |
| Drug Interactions | – Contraindicated with MAOIs – Caution with SSRIs, SNRIs, triptans, lithium, St. John’s Wort (↑ serotonin syndrome risk) – Strong CYP3A4 inhibitors (e.g., ketoconazole) ↑ drug levels – CYP3A4 inducers (e.g., carbamazepine) ↓ effectiveness |
| Storage | Store at 20°C–25°C (68°F–77°F); protect from moisture and light |
Common Side Effects
Like all medications, Fetzima (Levomilnacipran) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Nausea
- Constipation
- Increased sweating
- Rapid heartbeat (tachycardia)
- Difficulty urinating
- Dizziness or headache
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Fetzima (Levomilnacipran)?
You can order Fetzima (Levomilnacipran) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
