FemHRT (Ethinyl Estradiol/ Norethindrone)
FemHRT (Ethinyl Estradiol/ Norethindrone)
FemHRT is a prescription hormone therapy that combines ethinyl estradiol (estrogen) and norethindrone (progestin). It is designed to help women manage the symptoms of menopause, such as hot flashes and night sweats, while also protecting the uterus from risks associated with estrogen-only therapy. FemHRT may also support bone health and prevent postmenopausal osteoporosis.
Why Choose FemHRT (Ethinyl Estradiol/ Norethindrone)?
- Relieves common menopausal symptoms like hot flashes, mood changes, and night sweats.
- Helps reduce vaginal dryness and discomfort linked to menopause.
- Protects the uterine lining from abnormal growth caused by estrogen alone.
- Supports bone strength and helps lower the risk of osteoporosis in postmenopausal women.
- Convenient once-daily oral tablet for easy use.
How to Use FemHRT (Ethinyl Estradiol/ Norethindrone)?
- Take FemHRT exactly as prescribed by your healthcare provider.
- Swallow one tablet daily, ideally at the same time each day.
- Do not skip doses; if a dose is missed, take it as soon as remembered unless it’s almost time for the next dose.
- Regularly schedule check-ups with your doctor to evaluate benefits, side effects, and ongoing needs.
- Maintain a healthy lifestyle (balanced diet, exercise, no smoking) to enhance treatment benefits.
Important Safety Information about FemHRT
- Not recommended for women with a history of breast cancer, uterine cancer, or unexplained vaginal bleeding.
- Avoid use if you have blood clots, stroke, heart attack, or liver disease.
- Smoking while using estrogen-containing therapies increases the risk of blood clots and cardiovascular events.
- Regular breast exams, pelvic exams, and monitoring are advised during therapy.
- Inform your doctor of all medications and supplements to avoid interactions.
Fact Table
| Facts | Details |
| Brand Name | FemHRT |
| Generic Name | Ethinyl Estradiol / Norethindrone |
| Drug Class | Combination Hormone Therapy (Estrogen + Progestin) |
| Formulation | Oral tablets |
| Indication / Uses | – Relief of vasomotor symptoms of menopause (hot flashes, night sweats) – Treatment of vaginal dryness, itching, and burning due to menopause – Prevention of postmenopausal osteoporosis |
| Mechanism of Action | – Ethinyl Estradiol (Estrogen): Replaces declining estrogen levels, alleviating menopausal symptoms. – Norethindrone (Progestin): Protects uterine lining from hyperplasia caused by estrogen. |
| Administration | – Oral, once daily – Take at the same time each day |
| Onset of Effect | Symptom relief usually noticeable within a few weeks |
| Duration of Therapy | Lowest effective dose for the shortest duration consistent with treatment goals |
| Contraindications | – Breast cancer or estrogen-dependent tumors – Active or history of blood clots (DVT, PE) – Stroke or heart attack – Liver disease – Unexplained vaginal bleeding – Known or suspected pregnancy |
| Warnings & Precautions | – Increases risk of blood clots, stroke, and heart attack (especially in smokers >35 years) – May increase risk of breast cancer, ovarian cancer, and endometrial cancer – Requires regular breast and pelvic exams – Use with caution in patients with gallbladder disease, high blood pressure, or diabetes |
| Common Side Effects | – Breast tenderness/swelling – Nausea – Headache – Bloating – Mood changes – Irregular vaginal bleeding or spotting |
| Drug Interactions | – CYP3A4 inducers (e.g., rifampin, phenytoin, carbamazepine) may reduce effectiveness – Some antibiotics, antifungals, and anticonvulsants may interfere – May interact with thyroid medications, corticosteroids, or anticoagulants (e.g., warfarin) |
| Storage | Store at room temperature (20–25°C / 68–77°F), protect from moisture and light |
Common Side Effects
Like all medications, FemHRT (Ethinyl Estradiol/ Norethindrone) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Breast tenderness or swelling
- Mild nausea or stomach upset
- Headaches or migraines
- Bloating or weight changes
- Mood swings or irritability
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy FemHRT (Ethinyl Estradiol/ Norethindrone)?
You can order FemHRT (Ethinyl Estradiol/ Norethindrone) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
