Clopixol Depot (Zuclopenthixol Acetate)

Clopixol Depot
Zuclopenthixol Acetate

Source:
Clopixol Depot
Zuclopenthixol Acetate

Source:

 

Clopixol Depot (Zuclopenthixol Acetate)

Frequently Asked Questions

  1. What is Clopixol used for?

    Clopixol is mainly prescribed for managing schizophrenia and other psychotic disorders, especially during acute psychotic episodes and for long-term symptom management. It’s also used to treat episodes of mania in bipolar disorder.

  2. How does Clopixol work?

    Clopixol works by blocking dopamine receptors, specifically D1 and D2, which helps balance chemicals in the brain responsible for psychosis and mood disorders, reducing symptoms like hallucinations and agitation.

  3. What forms of Clopixol are available?

    Clopixol comes in tablet form and as injectable solutions. The injections are available as Acuphase for acute treatment and Depot for long-lasting effects, allowing maintenance doses once every 1-4 weeks.

  4. How long does Clopixol stay in the body?

    The tablet form of Clopixol has a half-life of about 20 hours, whereas the Depot injection can remain active for up to 19 days, providing a more gradual release over time.

  5. Are there any side effects of Clopixol?

    Yes, while most side effects are mild (like dizziness, dry mouth, and drowsiness), some other ones include involuntary muscle movements, fever, confusion, and a condition called neuroleptic malignant syndrome. Always report any troubling symptoms to your doctor immediately.

  6. Can I consume alcohol while on Clopixol?

    It’s best to avoid alcohol while taking Clopixol, as it can heighten side effects like drowsiness and dizziness, potentially leading to dangerous situations.

  7. Are there any drugs or conditions that interact with Clopixol?

    Clopixol can interact with various medications, including antihypertensives, anticholinergics, and CNS depressants. Additionally, conditions like heart disease, liver or kidney issues, and Parkinson’s disease may require adjustments or caution.

  8. Can Clopixol affect my ability to drive?

    Yes, Clopixol may cause drowsiness or blurred vision, which can impair your driving and machinery operation. It’s essential to understand how Clopixol affects you before engaging in these activities.

  9. What lifestyle adjustments should I consider while on Clopixol?

    Avoid excessive sunlight, as Clopixol can make your skin more sensitive. Also, maintain regular doctor visits for monitoring and any required blood tests to assess treatment progress.

  10. What are the overdose symptoms of Clopixol?

    Overdose symptoms may include extreme drowsiness, coma, convulsions, and even shock. Seek immediate medical help if an overdose is suspected, as urgent treatment may be required.

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References
Clopixol [package insert]. Citywest Business Park, Citywest: Lundbeck (Ireland) Limited; 2020.

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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