Climara (Estradiol Hemihydrate)

 

Climara (Estradiol Hemihydrate)

Climara is a transdermal patch designed to provide estrogen therapy through the gradual release of estradiol hemihydrate. It is primarily used to address symptoms associated with menopause, such as hot flashes, night sweats, and vaginal dryness. The Climara patch delivers a consistent dose of estrogen directly into your bloodstream, offering a convenient and effective way to manage menopausal symptoms and support overall hormone balance.

Why Choose Climara (Estradiol Hemihydrate)?

• Helps reduce the frequency and severity of hot flashes and night sweats
• Provides relief from vaginal dryness, itching, and irritation
• May support the prevention of osteoporosis in postmenopausal women
• Convenient once-a-week application
• Delivers a steady, controlled dose of estradiol over 7 days

How to Use Climara (Estradiol Hemihydrate)?

• Apply: Place the patch on a clean, dry area of your lower abdomen or buttocks. Avoid placing it near the breasts.
• Replace: Change the patch once a week (every 7 days) to maintain continuous estrogen levels.
• Rotate: Apply the patch to a different skin site each time to reduce skin irritation.
• Press: Ensure the patch is pressed firmly into place for 10 seconds to secure it properly.
• Dispose: Safely dispose of the used patch by folding it in half, sticky side in, and discarding it out of reach of children and pets.

Important Safety Information about Climara

• Not suitable for women with a history of hormone-sensitive cancers, such as breast or uterine cancer.
• Should not be used if you have a history of blood clots, stroke, or certain heart conditions.
• Climara is not a contraceptive and does not protect against pregnancy.
• Inform your doctor of any other medications you are taking, as they may interact with estrogen therapy.

Fact Table

 

Facts	Details
Product Name	Climara (Estradiol Hemihydrate)
Active Ingredient	Estradiol Hemihydrate
Strengths Available	0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, 0.1 mg/day
Indications	Menopausal symptoms (hot flashes, vaginal dryness), prevention of osteoporosis
Mechanism of Action	Replenishes estrogen levels in postmenopausal women, reducing symptoms
Dosage Form	Once-weekly patch
Route of Administration	Transdermal (applied to the skin)
Application Site	Lower abdomen or buttocks (avoid breast area)
Duration of Use	As prescribed by a healthcare provider
Onset of Action	Symptom relief may begin within a few weeks
Precautions	Do not use if you have a history of hormone-sensitive cancers, blood clots, or liver disease, or are pregnant
Important Warnings	Increases risk of cardiovascular events, breast cancer, stroke, and blood clots
Common Side Effects	Skin irritation at the application site, headache, breast tenderness, nausea
Drug Interactions	Anticoagulants, corticosteroids, thyroid hormones, enzyme-inducing drugs (e.g., certain anticonvulsants)
Storage Instructions	Store at room temperature, keep away from direct heat and sunlight
Who Should Not Use	Pregnant women, women with undiagnosed vaginal bleeding, or a history of hormone-sensitive cancers
FDA Approval Status	Approved for hormone replacement therapy

Common Side Effects

Like all medications, Climara (Estradiol Hemihydrate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Skin irritation or redness at the application site
• Breast tenderness or enlargement
• Headaches or migraines
• Nausea or upset stomach

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Climara (Estradiol Hemihydrate)?

You can order Climara (Estradiol Hemihydrate) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.