Accolate (Zafirlukast)

 

Accolate (Zafirlukast)

Accolate (Zafirlukast) is an oral prescription medication used to manage asthma symptoms by reducing inflammation in the airways. It belongs to a class of medicines called leukotriene receptor antagonists, which help prevent wheezing, shortness of breath, and asthma attacks when taken regularly. Accolate is not meant for immediate relief of sudden asthma symptoms but is effective for long-term control.

Why Choose Accolate (Zafirlukast)?

• Helps prevent asthma attacks and breathing difficulties.
• Reduces airway inflammation by blocking leukotrienes.
• Taken orally for convenient daily management.
• Improves overall lung function when used as prescribed.
• Can reduce the need for rescue inhalers with consistent use.

How to Use Accolate (Zafirlukast)?

• Take Accolate exactly as prescribed by your healthcare provider.
• Usually taken twice daily on an empty stomach (1 hour before or 2 hours after meals).
• Do not use Accolate to treat sudden asthma attacks, always carry a rescue inhaler for emergencies.
• Keep taking the medication regularly, even if you feel well.
• Store in a cool, dry place away from direct light and moisture.

Important Safety Information about Accolate

• Inform your doctor if you have a history of liver disease before starting Accolate.
• Regular blood tests may be needed to monitor liver function.
• Do not suddenly stop or reduce other asthma medications without medical advice.
• Use caution if taking other prescription drugs, especially warfarin or erythromycin.
• Not recommended for children under 5 years of age unless specifically directed by a physician.

Fact Table

 

Facts	Details
Brand Name	Accolate
Generic Name	Zafirlukast
Drug Class	Leukotriene receptor antagonist (LTRA)
Indication / Uses	Long-term management and prevention of asthma symptoms (wheezing, shortness of breath, asthma attacks). Not for acute asthma relief.
Mechanism of Action	Blocks leukotriene receptors, preventing airway inflammation, tightening, and mucus production.
Dosage Forms	Oral tablets
Strengths Available	10 mg, 20 mg tablets
Typical Adult Dosage	20 mg taken twice daily, on an empty stomach (1 hour before or 2 hours after meals)
Pediatric Use	Approved for children 5 years and older (10 mg twice daily). Not recommended for children under 5.
Onset of Action	Gradual, requires regular use; not effective for sudden asthma attacks
Administration Guidelines	– Take on an empty stomach – Consistent daily use required – Do not use as a rescue medication
Contraindications	– Hypersensitivity to zafirlukast or any tablet component – Patients with hepatic impairment or liver disease (risk of hepatotoxicity)
Warnings & Precautions	– Monitor liver function (risk of liver injury) – May interact with drugs like warfarin, theophylline, erythromycin – Rare cases of Churg-Strauss syndrome reported
Drug Interactions	– Warfarin: may increase INR (bleeding risk) – Theophylline: altered clearance – Erythromycin: may reduce zafirlukast levels – Aspirin/NSAIDs: can worsen asthma in sensitive patients
Common Side Effects	– Headache – Nausea – Diarrhea – Abdominal pain – Flu-like symptoms
Storage	Store at room temperature (20–25°C), away from light and moisture
Special Notes	– Not a substitute for inhaled corticosteroids or rescue inhalers – Continuous use is required for effectiveness

Common Side Effects

Like all medications, Accolate (Zafirlukast) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Headache
• Nausea or upset stomach
• Diarrhea
• Flu-like symptoms (tiredness, fever, muscle aches)

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Accolate (Zafirlukast)?

You can order Accolate (Zafirlukast) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.