You should avoid taking Zoloft if you meet any of the following conditions:

  • If you are currently taking a monoamine oxidase inhibitor (MAOI), or if you are uncertain whether you are taking an MAOI, including the antibiotic linezolid, consult your healthcare provider or pharmacist.
  • If you have taken an MAOI within 2 weeks of discontinuing Zoloft unless directed otherwise by your healthcare provider.
  • If you have ceased using an MAOI within the last 2 weeks unless directed otherwise by your healthcare provider.
  • If you are taking any other medications that contain sertraline (such as sertraline HCl or sertraline hydrochloride).
  • If you are using the antipsychotic medication pimozide (Orap®), this can lead to serious heart problems.
  • If you have an allergy to sertraline or any of the ingredients in Zoloft. You can find a comprehensive list of Zoloft’s ingredients at the end of the Medication Guide.
  • If you are taking Antabuse® (disulfiram) in its liquid form due to the alcohol content, it is advisable to avoid Zoloft.
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