Daraprim, known by its generic name pyrimethamine, is an antiparasitic medication. It’s primarily used to treat toxoplasmosis, a serious infection caused by the Toxoplasma parasite. This condition can occur in the body, brain, or eyes and is particularly dangerous for people with HIV infection. Daraprim is also used to treat and prevent certain types of malaria, although it’s usually not the first choice for malaria prevention in travelers.