The active ingredient in Zoloft is sertraline hydrochloride. In addition to the active ingredient, Zoloft tablets contain the following inactive ingredients:

  • Dibasic calcium phosphate dihydrate
  • D&C Yellow 10 aluminum lake (in 25 mg tablet)
  • FD&C Blue 1 aluminum lake (in 25 mg tablet)
  • FD&C Red Forty aluminum lake (in 25 mg tablet)
  • FD&C Blue 2 aluminum lake (in 50 mg tablet)
  • Hydroxypropyl cellulose
  • Hypromellose
  • Magnesium stearate
  • Microcrystalline cellulose
  • Polyethylene glycol
  • Polysorbate 80
  • Sodium starch glycolate
  • Synthetic yellow iron oxide used in 100 mg tablet
  • Titanium dioxide

The oral solution of Zoloft contains the following inactive ingredients:

  • Glycerin
  • Alcohol (12%)
  • Menthol
  • Butylated hydroxytoluene (BHT)
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