Myrbetriq is not suitable for individuals who are allergic to mirabegron or any of the inactive ingredients in the medication. If you are pregnant or breastfeeding, it's important to consult your doctor before considering Myrbetriq. People with end-stage renal disease, severe kidney problems, or severe uncontrolled hypertension should avoid this medication. Children under three years of age should not take Myrbetriq.