Ziac (Bisoprolol Fumarate, Hydrochlorothiazide)

Ziac
Bisoprolol Fumarate, Hydrochlorothiazide

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Ziac (Bisoprolol Fumarate, Hydrochlorothiazide)

Ziac (Bisoprolol Fumarate, Hydrochlorothiazide)

Ziac combines the benefits of Bisoprolol Fumarate with Hydrochlorothiazide, providing a dual-action treatment for high blood pressure. Ziac effectively decreases blood pressure by combining Bisoprolol’s heart rate-lowering properties with Hydrochlorothiazide’s fluid-reducing actions, lowering the risk of stroke and heart attack.

Why Choose Ziac (Bisoprolol Fumarate, Hydrochlorothiazide)?

  • Dual-Action Formula: Controls blood pressure through two methods, allowing for effective hypertension management.

  • Improved compliance: Combines two drugs into a single pill, simplifying the treatment routine.

  • Versatile Dosage Options: Available in a variety of strengths to fit unique patient needs and allow for dosage adjustments.

  • Reduces the risk of cardiovascular events: Reduces the risk of problems caused by high blood pressure, such as stroke and heart disease.

How to Use Ziac (Bisoprolol Fumarate, Hydrochlorothiazide)?

  • Take Ziac precisely as directed by your healthcare provider.

  • Can be taken with or without a meal.

  • It is critical to continue taking Ziac even if you are feeling fine because high blood pressure frequently has no symptoms.

  • Do not stop using this medication without first visiting your doctor.

Important Safety Information about Ziac

  • Ziac is not suitable for everyone. Do not use if you are allergic to bisoprolol, hydrochlorothiazide, or any of the other substances in the product.
  • Before using Ziac, tell your doctor about your medical history, especially if you have kidney or liver problems, diabetes, or gout.

  • Before using this product, pregnant or breastfeeding women should check with their healthcare provider.

Fact Table for Ziac

Generic Name Bisoprolol Fumarate and Hydrochlorothiazide

Brand Name

Ziac
Drug Class Beta-blocker (Bisoprolol Fumarate); Thiazide Diuretic (Hydrochlorothiazide)

FDA Approval

Yes (for the treatment of hypertension)

Indications Management of hypertension (high blood pressure)

Mechanism of Action

Bisoprolol reduces heart rate and contractility; Hydrochlorothiazide increases the excretion of sodium and water
Dosage Forms
Oral tablets
Common Dosages

Varies by the patient; typically once daily

Key Side Effects Dizziness, fatigue, nausea, slow heartbeat, diarrhea, hypotension
Contraindications Severe chronic heart failure, acute heart failure, cardiogenic shock, severe bradycardia, severe renal or hepatic impairment, hypersensitivity to components

Special Considerations Monitor electrolytes and renal function; caution in patients with diabetes, gout, or asthma/span>
Pregnancy Category Consult your healthcare provider

Alcohol Interaction Alcohol may increase certain side effects of Ziac; consult with a healthcare provider

Possible Drug Interactions

May interact with other blood pressure medications, lithium, non-steroidal anti-inflammatory drugs (NSAIDs), certain diabetes medications

Storage Instructions

Store at room temperature, away from moisture and heat

Common Side Effects of Ziac

Like all medications, Ziac (Bisoprolol Fumarate, Hydrochlorothiazide) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Dizziness
  • Fatigue
  • Nausea
  • Slow heartbeat
  • Diarrhea
  • Hypotension

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Ziac (Bisoprolol Fumarate, Hydrochlorothiazide)?

You can order Ziac (Bisoprolol Fumarate, Hydrochlorothiazide) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

Frequently Asked Questions

  1. What about pregnancy and breastfeeding?

    If you’re pregnant, planning to be, or breastfeeding, have a chat with your doctor. The safety of Ziac for unborn babies and nursing infants isn’t fully established, so it’s best to err on the side of caution.

  2. Can other medications affect Ziac?

    Absolutely, Ziac might interact with other drugs like insulin, oral diabetes medicine, or NSAIDs, just to name a few. Always inform your healthcare provider about all the medications and supplements you’re taking to avoid unwanted interactions.

  3. What are the possible side effects?

    While some people breeze through with no side effects, others might experience dizziness, weakness, or cough, among others. Serious side effects like chest pain, breathing issues, severe skin reactions, or liver problems are less common but require urgent medical attention.

  4. What if I miss a dose or overdose?

    If you miss a dose, take it as soon as you remember, unless it’s almost time for the next one.If you overdose on Ziac, immediately seek medical help. Overdose symptoms can include confusion, leg cramps, numbness, slow heartbeats, or even fainting.

  5. How should Ziac be taken?

    Ziac is a once-a-day medication, but follows your doctor’s prescription to the letter. This might include adjusting the dose depending on how your body responds. And remember, stopping Ziac suddenly is not advisable; if you need to stop, your doctor will guide you on gradually reducing your dosage.

  6. Are there any precautions to consider?

    Yes, indeed. For starters, if you have diabetes, keep an eye on your blood sugar levels because Ziac can mask hypoglycemia symptoms. It’s also wise to avoid becoming too hot or dehydrated. And for those planning surgery, make sure your doctor knows you’re on Ziac, as you might need to pause your dosage.

  7. Who shouldn’t take Ziac?

    If you’re someone who can’t urinate or has severe heart issues like “sick sinus syndrome,” “AV block,” serious heart failure, or very slow heartbeats that cause fainting, Ziac might not be the right match for you. Also, it’s a no-go if you’re allergic to either bisoprolol or hydrochlorothiazide.

  8. What is Ziac?

    Ziac combines the powers of hydrochlorothiazide, a thiazide diuretic (or water pill), and bisoprolol, a beta-blocker. This dynamic duo teams up to tackle high blood pressure by making you urinate more (which drops your blood pressure) and slowing down your heartbeat.

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References
Ziac [package insert].Pomona, New York: Duramed Pharmaceuticals;2011.

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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