Canada Post & FedEx shipping 
Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)
Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)
Xigduo combines dapagliflozin and metformin to help control blood sugar levels in adults with type 2 diabetes. Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, reduces glucose reabsorption in the kidneys, while metformin, a biguanide, decreases glucose production in the liver and improves insulin sensitivity.
Why Choose Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)?
- Helps control blood sugar levels in type 2 diabetes
- Combines two effective diabetes management agents in one tablet
- May aid in weight loss by reducing excess glucose reabsorption
- Supports cardiovascular health in patients with heart disease risk
- Reduces the risk of complications associated with prolonged high blood sugar
How to Use Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)?
- Take as directed by your healthcare provider: Follow prescribed doses and timing for optimal effectiveness.
- Take with food: Reduces stomach upset and improves absorption.
- Hydration: Drink plenty of water throughout the day, especially in warmer climates or during exercise.
- Avoid alcohol: Alcohol can interact with metformin, increasing the risk of lactic acidosis.
Important Safety Information about Xigduo
- Storage: Store at room temperature, away from moisture and heat. Keep in a tightly closed container.
- Precautions: Not suitable for those with severe kidney disease or diabetic ketoacidosis.
- Regular Monitoring: Regular blood sugar and kidney function tests are recommended.
- Not for type 1 diabetes: Xigduo is intended only for type 2 diabetes management.
Fact Table
| Facts | Details |
| Generic Name | Dapagliflozin Propanediol Monohydrate / Metformin Hydrochloride |
| Brand Name | Xigduo |
| Drug Class | Antidiabetic combination (SGLT2 inhibitor and biguanide) |
| Primary Use | Type 2 Diabetes Management |
| Formulation | Oral tablets |
| Strengths Available | Various combinations of dapagliflozin (5 mg, 10 mg) and metformin (500 mg, 1000 mg) |
| Mechanism of Action | – Dapagliflozin: Inhibits sodium-glucose co-transporter 2 (SGLT2), reducing glucose reabsorption in the kidneys – Metformin: Reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues |
| Benefits | – Helps lower blood glucose levels in adults with type 2 diabetes – Supports weight management and cardiovascular health – Lowers the risk of complications associated with type 2 diabetes |
| Recommended Dosage | – Typically once or twice daily with meals, as prescribed by a healthcare provider |
| How to Take | – Take orally with food to minimize gastrointestinal side effects |
| Onset of Action | Dapagliflozin: Within 24 hours; Metformin: Effects may be observed within 48 hours and stabilize over several weeks |
| Duration of Action | Lasts up to 24 hours, depending on dose and individual metabolic rate |
| Storage Conditions | Store at room temperature, away from moisture and heat; keep container tightly closed |
| Special Precautions | – Not suitable for individuals with severe kidney disease, metabolic acidosis, or diabetic ketoacidosis – Use cautiously in patients with liver impairment – Avoid excessive alcohol intake while using this medication |
| Drug Interactions | – May interact with alcohol, insulin, certain diuretics, and medications that affect kidney function – Caution with drugs that lower blood sugar (risk of hypoglycemia) |
| Possible Side Effects | – Common: Diarrhea, nausea, increased urination, stomach discomfort |
| Approval Status | Approved by FDA for type 2 diabetes management in adults |
Common Side Effects
Like all medications, Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Diarrhea, nausea, or stomach discomfort
- Increased urination due to glucose excretion
- Low blood sugar (hypoglycemia), especially if used with other diabetes medications
- Risk of dehydration in certain cases
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)?
You can order Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
4 INSTALLMENTS, 6 WEEKS, 0% INTEREST
PharmaServe now offers you the option to make 4-interest-free payments by credit card once your order is confirmed using
Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
OZEMPIC: Huge price drop limited stock, limited time opportunity. 
MOUNJARO (12.5mg): Save up to 70% Use code MN12MG for an additional 10% off for 12.5mg. Chat now to order and save up to $90 or