Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)
Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)
Xigduo combines dapagliflozin and metformin to help control blood sugar levels in adults with type 2 diabetes. Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, reduces glucose reabsorption in the kidneys, while metformin, a biguanide, decreases glucose production in the liver and improves insulin sensitivity.Why Choose Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)?
- Helps control blood sugar levels in type 2 diabetes
- Combines two effective diabetes management agents in one tablet
- May aid in weight loss by reducing excess glucose reabsorption
- Supports cardiovascular health in patients with heart disease risk
- Reduces the risk of complications associated with prolonged high blood sugar
How to Use Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)?
- Take as directed by your healthcare provider: Follow prescribed doses and timing for optimal effectiveness.
- Take with food: Reduces stomach upset and improves absorption.
- Hydration: Drink plenty of water throughout the day, especially in warmer climates or during exercise.
- Avoid alcohol: Alcohol can interact with metformin, increasing the risk of lactic acidosis.
Important Safety Information about Xigduo
- Storage: Store at room temperature, away from moisture and heat. Keep in a tightly closed container.
- Precautions: Not suitable for those with severe kidney disease or diabetic ketoacidosis.
- Regular Monitoring: Regular blood sugar and kidney function tests are recommended.
- Not for type 1 diabetes: Xigduo is intended only for type 2 diabetes management.
Fact Table
| Facts | Details |
| Generic Name | Dapagliflozin Propanediol Monohydrate / Metformin Hydrochloride |
| Brand Name | Xigduo |
| Drug Class | Antidiabetic combination (SGLT2 inhibitor and biguanide) |
| Primary Use | Type 2 Diabetes Management |
| Formulation | Oral tablets |
| Strengths Available | Various combinations of dapagliflozin (5 mg, 10 mg) and metformin (500 mg, 1000 mg) |
| Mechanism of Action | - Dapagliflozin: Inhibits sodium-glucose co-transporter 2 (SGLT2), reducing glucose reabsorption in the kidneys - Metformin: Reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues |
| Benefits | - Helps lower blood glucose levels in adults with type 2 diabetes - Supports weight management and cardiovascular health - Lowers the risk of complications associated with type 2 diabetes |
| Recommended Dosage | - Typically once or twice daily with meals, as prescribed by a healthcare provider |
| How to Take | - Take orally with food to minimize gastrointestinal side effects |
| Onset of Action | Dapagliflozin: Within 24 hours; Metformin: Effects may be observed within 48 hours and stabilize over several weeks |
| Duration of Action | Lasts up to 24 hours, depending on dose and individual metabolic rate |
| Storage Conditions | Store at room temperature, away from moisture and heat; keep container tightly closed |
| Special Precautions | - Not suitable for individuals with severe kidney disease, metabolic acidosis, or diabetic ketoacidosis - Use cautiously in patients with liver impairment - Avoid excessive alcohol intake while using this medication |
| Drug Interactions | - May interact with alcohol, insulin, certain diuretics, and medications that affect kidney function - Caution with drugs that lower blood sugar (risk of hypoglycemia) |
| Possible Side Effects | - Common: Diarrhea, nausea, increased urination, stomach discomfort |
| Approval Status | Approved by FDA for type 2 diabetes management in adults |
Common Side Effects
Like all medications, Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.- Diarrhea, nausea, or stomach discomfort
- Increased urination due to glucose excretion
- Low blood sugar (hypoglycemia), especially if used with other diabetes medications
- Risk of dehydration in certain cases
How Can You Buy Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin)?
You can order Xigduo (Dapagliflozin Propanediol Monohydrate/Metformin) using these methods on our website:- Order Online
- Order by Phone
- Order by Fax
- Order your refills
