Vagifem
Product Review
Vagifem
Vagifem (estradiol vaginal tablets) is a prescription medication specifically designed to provide relief from vaginal dryness and discomfort experienced by peri- or post-menopausal women. The active ingredient, estradiol, is a form of estrogen that helps to replenish the declining estrogen levels in the body, which are responsible for vaginal symptoms.
Why Choose Vagifem?
Vagifem works by releasing estradiol, a form of estrogen, directly into the vaginal tissue. This helps to maintain and improve the health of vaginal tissues by increasing natural moisture and elasticity. By delivering the hormone directly to the affected area, Vagifem can provide relief from the symptoms of vaginal atrophy while using a lower dose of estrogen compared to oral or systemic hormone therapy.
How to use Vagifem?
Vagifem is a small, easy-to-use vaginal tablet that comes with a preloaded, single-use applicator. It is typically used once daily for the first two weeks, followed by a maintenance dose of twice a week. Always follow your healthcare provider’s instructions and read the patient information leaflet provided with the medication.
Important Safety Information about Vagifem
Before using Vagifem, inform your healthcare provider if you have a history of blood clots, heart disease, liver problems, or any condition that makes you more prone to blood clots. Vagifem should not be used by women with undiagnosed abnormal vaginal bleeding, a history of breast cancer, or known or suspected estrogen-dependent neoplasia. It is also not recommended for women who are pregnant or breastfeeding.
Fact Table of Vagifem
| Fact | Fact Details |
| Generic Name | Estradiol vaginal tablets |
| Brand Name | Vagifem |
| Used For | Vaginal dryness and discomfort |
| Symptoms Addressed | Vaginal atrophy, itching, irritation |
| Drug Class | Estrogen replacement therapy |
| Administration | Vaginal tablet with applicator |
| Initial Dosage | Once daily for the first two weeks |
| Maintenance Dosage | Twice a week |
| Contraindications | Undiagnosed abnormal vaginal bleeding, history of breast cancer, known or suspected estrogen-dependent neoplasia |
| Pregnancy and Breastfeeding | Not recommended |
| Prescription Required | Yes |
Common Side Effects of Vagifem
Some common side effects of Vagifem may include
- Upper respiratory tract infection
- Headache
- Abdominal pain
- Back pain
- Genital pruritus
- Moniliasis
- Vulvovaginal mycotic infection
- Diarrhea
If any of these side effects persist or worsen, contact your healthcare provider immediately.
How Can You Buy Vagifem?
You can order Vagifem using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
Product Review
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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