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Silenor (Doxepin)

Silenor
Doxepin Hydrochloride
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Silenor (Doxepin)

Silenor (Doxepin)

Silenor® is a sleep aid that helps those who suffer from insomnia fall asleep faster and stay asleep longer. The active ingredient, Doxepin, is a tricyclic antidepressant repurposed at lower doses to provide a solution for sleep disturbances without the dependency risks associated with other sleep medications.

Why Choose Silenor (Doxepin)?

  • Non-Habit Forming: Unlike many sleep aids, Silenor® does not have the potential for abuse or addiction.
  • Maintains Sleep Architecture: Helps you stay asleep by blocking histamine receptors.
  • Minimal Next-Day Drowsiness: Designed to minimize the risk of grogginess the following day.
  • Safe for Long-Term Use: FDA-approved for nightly use without a decrease in effectiveness over time.

How to Use Silenor (Doxepin)?

  • Take one tablet with water, 30 minutes before bedtime.
  • Follow your healthcare provider’s instructions regarding the proper dosage.
  • Do not take more than the prescribed dosage.

Important Safety Information about Silenor

  • Do not use Silenor® if you are allergic to doxepin or any of the other ingredients in the product.
  • Avoid alcohol, as it can increase some side effects of doxepin.
  • Silenor® may impair your thinking or reactions. Be cautious if you drive or do anything that requires you to be alert.
  • Discuss your health conditions and medication list with your doctor to ensure Silenor® is safe for you.

Fact Table for Silenor

Facts Details
Generic Name Doxepin
Brand Name Silenor
Drug Class Tricyclic antidepressant (TCA)
FDA Approved Yes, specifically for the treatment of insomnia
Indications Treatment of insomnia characterized by difficulty maintaining sleep
Available Dosage Forms Oral tablets
Common Dosages 3 mg, 6 mg
Administration Oral, taken 30 minutes before bedtime
Mechanism of Action Antagonist at histamine H1 receptors; helps to maintain sleep by reducing wakefulness
Half-Life 8-24 hours (varies by individual metabolic rate)
Key Benefits Non-habit forming, minimal next-day drowsiness, maintains sleep architecture
Common Side Effects Drowsiness, upper respiratory tract infection, nausea
Contraindications Hypersensitivity to doxepin, glaucoma, urinary retention
Warnings Avoid alcohol, may impair mental or physical abilities needed for performing hazardous tasks
Interactions Can interact with MAO inhibitors, alcohol, and other CNS depressants
Patient Considerations Caution in elderly patients, those with a history of substance abuse, or those with certain medical conditions like heart disease or bipolar disorder
Regulatory Status FDA-approved for the management of insomnia

Common Side Effects of Silenor

Like all medications, Silenor (Doxepin) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Drowsiness
  • Upper respiratory tract infection
  • Nausea

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Silenor (Doxepin)?

You can order Silenor (Doxepin) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

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Questions?


Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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