Rowasa (Mesalamine)

 

Rowasa (Mesalamine)

Rowasa (Mesalamine) is a prescription treatment used to help manage ulcerative colitis, a chronic inflammatory condition of the colon and rectum. It works by reducing inflammation in the lining of the intestine, relieving symptoms such as abdominal pain, rectal bleeding, and diarrhea. Rowasa is typically administered as a rectal enema, allowing the medication to directly target affected areas in the lower bowel for fast and effective relief.

Why Choose Rowasa (Mesalamine)?

• Helps reduce inflammation in the colon and rectum
• Provides targeted relief directly to the affected area
• Improves symptoms like rectal bleeding, urgency, and cramping
• Can support long-term remission in ulcerative colitis
• Non-steroidal formulation for fewer systemic effects

How to Use Rowasa (Mesalamine)?

• Use Rowasa exactly as prescribed by your healthcare provider.
• Shake the bottle well before use to ensure even distribution of the medication.
• Administer the enema at bedtime and try to retain it for at least 8 hours (or overnight) for best results.
• Lie on your left side while inserting the applicator tip gently into the rectum.
• Dispose of the used bottle safely after each application.
• Wash your hands thoroughly after use.

Important Safety Information about Rowasa

• Do not use Rowasa if you are allergic to mesalamine, salicylates, or any component of the formulation.
• Inform your doctor if you have kidney or liver problems before starting treatment.
• Regular blood and urine tests may be required to monitor your kidney function.
• Stop using and seek medical attention if you experience chest pain, shortness of breath, swelling, or rash.
• Keep the medication out of reach of children and store it at room temperature, away from heat and light.

Fact Table

 

Facts	Details
Brand Name	Rowasa
Generic Name	Mesalamine
Drug Class	Aminosalicylate (5-ASA)
Dosage Forms Available	Rectal enema (4 g/60 mL), Rectal suppository (1 g)
Route of Administration	Rectal
Indication	Treatment and maintenance of remission in mild to moderate ulcerative colitis, especially affecting the distal colon and rectum
Mechanism of Action	Mesalamine works locally in the colon to reduce inflammation by inhibiting cyclooxygenase and lipoxygenase pathways, which decreases prostaglandin and leukotriene synthesis.
Onset of Action	Improvement may be seen within 3–21 days of consistent use
Storage Conditions	Store at controlled room temperature (15°C–30°C / 59°F–86°F). Protect from freezing.
Key Benefits	– Targets inflammation directly in the lower colon and rectum – Helps relieve symptoms such as bleeding, diarrhea, and abdominal pain – Non-systemic, minimizing whole-body side effects
Important Safety Information	– For rectal use only; do not take orally – Discontinue if severe abdominal pain, cramps, or rash occurs – Use with caution in patients with renal or hepatic impairment – Report any signs of hypersensitivity or worsening symptoms
Common Side Effects	– Abdominal cramping or pain – Flatulence or bloating – Rectal discomfort – Headache – Nausea
Drug Interactions	– May interact with nephrotoxic drugs (e.g., NSAIDs, azathioprine) – Avoid combining with other mesalamine-containing products
Contraindications	– Known hypersensitivity to mesalamine or salicylates – Severe renal or hepatic impairment
Overdose Management	Supportive care; discontinue use and seek medical attention if large quantities are ingested
Availability	Prescription only

Common Side Effects

Like all medications, Rowasa (Mesalamine) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Mild abdominal cramps or discomfort
• Rectal irritation or pain
• Gas or bloating
• Headache
• Dizziness or fatigue

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Rowasa (Mesalamine)?

You can order Rowasa (Mesalamine) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.