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Rexulti (Brexpiprazole)
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Rexulti (Brexpiprazole)
Rexulti (Brexpiprazole) is an antipsychotic medication used to treat schizophrenia and as an adjunctive treatment for major depressive disorder (MDD) in adults. It works by balancing chemicals in the brain to improve mood, thinking, and behavior.
Why Choose Rexulti (Brexpiprazole)?
- Effective Treatment: Helps reduce the symptoms of schizophrenia and depression.
- Adjunctive Therapy: Can be used alongside other antidepressants for enhanced results.
- Improved Quality of Life: Aims to restore daily functioning and social interaction.
- Lower Risk of Side Effects: Offers a favorable side effect profile compared to other antipsychotics.
How to Use Rexulti (Brexpiprazole)?
- Consult Your Doctor: Always discuss your medical history and any current medications with your healthcare provider before starting Rexulti.
- Follow Prescribed Dosage: Take Rexulti exactly as prescribed; do not exceed the recommended dose.
- Take with or without Food: Rexulti can be taken with or without food as directed by your physician.
- Regular Check-ups: Attend follow-up appointments to monitor progress and any side effects.
Important Safety Information about Rexulti
- Not for Everyone: Rexulti is not suitable for individuals with a known allergy to brexpiprazole or any components of the medication.
- Caution in Elderly Patients: Increased risk of side effects in elderly patients with dementia-related psychosis.
- Drug Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking to avoid interactions.
Fact Table
| Facts | Details |
| Generic Name | Brexpiprazole |
| Brand Name | Rexulti |
| Drug Class | Atypical antipsychotic (second-generation antipsychotic) |
| Indications | Major Depressive Disorder (MDD) adjunct treatment, Schizophrenia |
| Mechanism of Action | Partial agonist at serotonin 5-HT1A and dopamine D2 receptors, antagonist at serotonin 5-HT2A receptors |
| Dosage Forms | Oral tablets |
| Strengths | 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg |
| Administration | Taken orally, once daily, with or without food |
| Common Side Effects | Weight gain, akathisia (restlessness), headache, drowsiness, dizziness |
| Use in Elderly | Increased risk of death in elderly patients with dementia-related psychosis |
| Interactions | Caution with other CNS depressants, certain antidepressants, and antifungals |
| Monitoring | Regular monitoring of mood, weight, and metabolic changes is recommended |
| FDA Approval Year | 2015 |
| Storage | Store at room temperature, away from moisture and heat |
Common Side Effects
Like all medications, Rexulti (Brexpiprazole) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Weight Gain
- Drowsiness or Fatigue
- A feeling of restlessness or the need to move
- Nausea or Vomiting
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Rexulti (Brexpiprazole)?
You can order Rexulti (Brexpiprazole) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
Product Review
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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