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Plaquenil (Hydroxychloroquine Sulfate)
Product Review
Plaquenil (Hydroxychloroquine Sulfate)
Plaquenil (Hydroxychloroquine Sulfate) is a medication primarily used to treat malaria, lupus erythematosus, and rheumatoid arthritis. It belongs to a class of medications known as antimalarials and works by interfering with the growth of parasites that cause malaria, as well as by reducing inflammation in autoimmune conditions like lupus and rheumatoid arthritis.
Why Choose Plaquenil (Hydroxychloroquine Sulfate)?
- Effective treatment for malaria: Plaquenil is widely recognized as an effective medication for the prevention and treatment of malaria caused by Plasmodium species.
- Management of autoimmune conditions: Plaquenil helps alleviate symptoms associated with lupus erythematosus and rheumatoid arthritis by reducing inflammation and joint pain.
- Well-tolerated: With proper dosage and administration, Plaquenil is generally well-tolerated by most patients, making it a suitable long-term treatment option.
- Versatile usage: Apart from its primary indications, Plaquenil is also prescribed off-label for various other conditions, including dermatological and rheumatological disorders.
How to Use Plaquenil (Hydroxychloroquine Sulfate)?
- Dosage may vary depending on the condition being treated, the patient’s weight, and medical history. It is essential to follow the dosage instructions provided by the healthcare professional.
- Plaquenil is usually taken orally with food or milk to prevent stomach upset.
- Patients are advised to continue taking Plaquenil regularly as prescribed, even if symptoms improve, to ensure optimal therapeutic benefits.
Important Safety Information about Plaquenil
- Inform the healthcare provider about any pre-existing medical conditions, allergies, or medications being taken before starting Plaquenil therapy.
- Regular eye examinations are recommended for patients on long-term Plaquenil treatment to monitor for potential ocular side effects.
- Caution is advised in patients with liver or kidney impairment, as dosage adjustments may be necessary.
- Avoid consuming alcohol while taking Plaquenil, as it may increase the risk of liver damage.
Fact Table
| Facts | Details |
| Generic Name | Hydroxychloroquine Sulfate |
| Brand Names | Plaquenil |
| Drug Type | Antimalarial, Disease-Modifying Antirheumatic Drug (DMARD) |
| Approved Uses | – Treatment of malaria- Treatment of lupus erythematosus- Treatment of rheumatoid arthritis |
| Off-label Uses | May be used in the treatment of other autoimmune conditions as directed by a doctor |
| Administration Route | Oral |
| Dosage Forms | Tablets, usually 200 mg |
| Common Dosage | Varies; typically 200-400 mg daily depending on the condition and patient response |
| Key Side Effects | – Nausea – Vomiting – Headache – Dizziness – Retinal damage (with long-term use) |
| Contraindications | – Known hypersensitivity to hydroxychloroquine or other 4-aminoquinoline compounds – Presence of retinal or visual field changes attributable to any 4-aminoquinoline compound |
| Precautions | – Regular eye examinations are recommended due to the risk of retinopathy – Caution in patients with gastrointestinal, neurological, or blood disorders – Use cautiously in patients with hepatic disease or alcoholism, or conjunction with known hepatotoxic drugs |
| Interactions | – Antacids and kaolin can reduce absorption of hydroxychloroquine – Hydroxychloroquine may enhance the effects of a hypoglycemic treatment – Cimetidine may increase plasma levels of hydroxychloroquine |
| Pregnancy Category | Category C (Risk not ruled out) |
| Mechanism of Action | Thought to inhibit the processing of antigens in the macrophage and other antigen-presenting cells; and also stabilizes lysosomal enzymes, inhibiting the synthesis of prostaglandins and other potentially inflammatory chemicals |
Common Side Effects
Like all medications, Plaquenil (Hydroxychloroquine Sulfate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Nausea
- Vomiting
- Headache
- Dizziness
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Plaquenil (Hydroxychloroquine Sulfate)?
You can order Plaquenil (Hydroxychloroquine Sulfate) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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