Ortho Evra (Ethinyl Estradiol/ Norelgestromin)
Ortho Evra (Ethinyl Estradiol/ Norelgestromin)
Ortho Evra is a prescription birth control patch that contains a combination of two hormones: Ethinyl Estradiol (a form of estrogen) and Norelgestromin (a form of progestin). It offers a convenient, weekly method of preventing pregnancy by releasing hormones directly through the skin into the bloodstream, providing effective contraceptive coverage.
Why Choose Ortho Evra (Ethinyl Estradiol/ Norelgestromin)?
- Convenient weekly application – Only needs to be changed once a week for three weeks, followed by a patch-free week.
- Highly effective – Provides over 99% effectiveness when used correctly.
- Non-invasive and discreet – Worn discreetly on the skin, avoiding the need for daily reminders or invasive procedures.
- Regulates menstrual cycles – Helps reduce irregular periods and can result in lighter, more predictable menstrual flow.
- May reduce PMS symptoms – Can alleviate symptoms like cramping and mood swings associated with menstruation.
How to Use Ortho Evra (Ethinyl Estradiol/ Norelgestromin)?
- Clean, dry, and hair-free areas such as the buttock, abdomen, upper outer arm, or upper back.
- Avoid areas that may be exposed to friction from tight clothing.
- Remove the protective liner and firmly press the patch on your chosen area.
- Hold in place for about 10 seconds to ensure proper adhesion.
- Apply a new patch on the same day each week for three consecutive weeks.
- Week 4 is patch-free to allow for a menstrual period.
- Fold the patch in half so it sticks to itself before discarding.
- Reapply a new patch immediately if it has been off for less than 24 hours.
- Use a backup contraceptive method if it has been off for more than 24 hours.
Important Safety Information about Ortho Evra
Do not use it if you:
- Are pregnant or suspect you might be pregnant.
- Smoke and are over 35 years old, as it increases the risk of serious cardiovascular events.
- Have a history of blood clots, stroke, or heart attack.
- Have liver disease or unexplained vaginal bleeding.
- Avoid prolonged exposure to heat or sunlight while wearing the patch, as it may affect the adhesive or hormone release.
Fact Table
| Facts | Details |
| Generic Name | Ethinyl Estradiol / Norelgestromin |
| Brand Name | Ortho Evra |
| Drug Class | Combination hormonal contraceptive (Estrogen + Progestin) |
| Dosage Form | Transdermal patch |
| Strength | Each patch contains: 6 mg Norelgestromin and 0.75 mg Ethinyl Estradiol. It releases approximately 150 mcg of Norelgestromin and 35 mcg of Ethinyl Estradiol per day. |
| Indication | Prevention of pregnancy |
| Application Schedule | – Apply a new patch once a week for 3 weeks. – No patch is worn during the 4th week to allow for a menstrual period. |
| Duration of Action | Weekly (7 days per patch) |
| Onset of Action | Within 24 hours of applying the patch |
| Common Side Effects | – Skin irritation at the application site – Nausea – Breast tenderness – Headache – Mood swings – Breakthrough bleeding |
| Storage Instructions | Store at room temperature (15°C to 30°C / 59°F to 86°F). Keep patches in their protective pouches until use. |
| Drug Interactions | – Antibiotics (e.g., Rifampin) – Anticonvulsants (e.g., Carbamazepine, Phenytoin) – St. John’s Wort – HIV medications |
| Precautions | – Avoid using on irritated or broken skin. – Do not expose the patch to excessive heat (e.g., saunas, hot tubs). |
| Mechanism of Action | Inhibits ovulation, thickens cervical mucus, and alters the endometrial lining to prevent pregnancy. |
| Effectiveness | Over 99% effective when used correctly. |
| Disposal Instructions | Fold the patch in half (sticky sides together) before discarding to prevent accidental hormone exposure. |
| FDA Approval | Approved by the FDA in November 2001 |
Common Side Effects
Like all medications, Ortho Evra (Ethinyl Estradiol/ Norelgestromin) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Mild skin irritation at the patch application site
- Nausea or vomiting
- Breast tenderness or discomfort
- Headaches
- Mood changes or irritability
- Menstrual spotting or breakthrough bleeding
If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Ortho Evra (Ethinyl Estradiol/ Norelgestromin)?
You can order Ortho Evra (Ethinyl Estradiol/ Norelgestromin) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
