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Orilissa (Elagolix Sodium)

  Orilissa (Elagolix Sodium)

Orilissa (Elagolix Sodium)

Orilissa (Elagolix Sodium) is an FDA-approved prescription medication used to manage moderate to severe pain associated with endometriosis. Orilissa works by reducing estrogen levels, which can help alleviate the pain and discomfort caused by endometriosis. Available in easy-to-swallow tablet form, Orilissa offers a non-surgical option for symptom relief, empowering women to reclaim comfort and quality of life with minimal disruption to daily activities.

Why Choose Orilissa (Elagolix Sodium)?

  • Effective Pain Relief: Specifically targets endometriosis-related pain, including pain during menstruation, pelvic pain, and pain during intercourse.
  • Non-Surgical Solution: Provides an alternative to surgical treatments, offering symptom management in a convenient tablet form.
  • Rapid Action: Can start relieving pain within 24 hours of the first dose for some users.
  • Two Dosage Options: Available in 150 mg once daily or 200 mg twice daily, allowing for tailored treatment based on severity and response.

How to Use Orilissa (Elagolix Sodium)?

  • Consult Your Doctor: Ensure Orilissa is appropriate for you based on your medical history and other medications.
  • Follow Prescribed Dosage: Take exactly as prescribed, either 150 mg once daily or 200 mg twice daily, depending on your doctor’s guidance.
  • Take with or without Food: Can be taken with meals or on an empty stomach based on personal preference.
  • Avoid Alcohol: Minimize alcohol consumption to prevent potential interactions.
  • Stay Consistent: Take doses at the same time each day for maximum effectiveness.

Important Safety Information about Orilissa

  • Not for Pregnancy: Do not use Orilissa if you are pregnant or planning to become pregnant, as it can harm an unborn baby.
  • Osteoporosis Risk: Long-term use may decrease bone density, so limit usage as directed by your doctor.
  • Interactions: Inform your healthcare provider of any other medications, especially hormonal birth control, as Orilissa may interact with certain drugs.
  • Mental Health Considerations: Some users may experience mood changes; notify your doctor if you have a history of depression or anxiety.

Fact Table

 
Facts Details
Medication Name Orilissa
Generic Name Elagolix Sodium
Formulation Oral Tablet
Strengths Available 150 mg (once daily) and 200 mg (twice daily)
Indication Treatment of moderate to severe pain associated with endometriosis
Mechanism of Action Gonadotropin-releasing hormone (GnRH) receptor antagonist; reduces estrogen levels to alleviate endometriosis pain
Dosage - 150 mg once daily (for up to 24 months) - 200 mg twice daily (for up to 6 months)
Administration Take orally, with or without food
Time to Effect Typically within 1–2 months of consistent use
Common Side Effects Hot flashes, headaches, nausea, mood changes, and sleep disturbances
Contraindications Pregnancy, osteoporosis, liver impairment
Precautions Monitor bone density; avoid in patients with a history of depression or liver issues
Storage Store at room temperature, 20°C to 25°C (68°F to 77°F)
FDA Approval Approved in July 2018
Prescription Required Yes

Common Side Effects

Like all medications, Orilissa (Elagolix Sodium) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
  • Hot Flashes
  • Headaches
  • Nausea
  • Mood Changes
  • Bone Density Loss
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Orilissa (Elagolix Sodium)?

You can order Orilissa (Elagolix Sodium) using these methods on our website:
  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills
Visit our How to order page.
Dr. Conor Sheehy, PharmD, BCPS

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.

Please note that due to government rules and regulations, orders may not exceed 3 months in supply.
Please call 1-800-258-0477 or email us if you have any questions or concerns.