Nozinan Injection (Levomepromazine Hydrochloride)

 

 

Nozinan Injection (Levomepromazine Hydrochloride)

Nozinan Injection (Levomepromazine Hydrochloride) is an antipsychotic and sedative medication used in hospital and palliative care settings. It helps manage severe pain, anxiety, agitation, and nausea in patients with terminal illnesses. Nozinan acts on the brain’s neurotransmitters to produce calming, antiemetic, and analgesic effects, improving overall comfort and quality of life for those requiring intensive symptom relief.

Why Choose Nozinan Injection (Levomepromazine Hydrochloride)?

• Provides effective relief from severe nausea and vomiting
• Helps manage agitation, restlessness, and distress in palliative care
• Offers strong sedative properties to support relaxation and comfort
• Can be used alongside opioid treatments to enhance pain control
• Reduces anxiety and promotes sleep in end-of-life care situations

How to Use Nozinan Injection (Levomepromazine Hydrochloride)?

• Administer only under medical supervision by a healthcare professional
• Given by intramuscular (IM) or intravenous (IV) injection as prescribed
• Ensure the correct dosage and dilution are followed according to the doctor’s directions
• Monitor for sedation and adjust dosage if excessive drowsiness occurs
• Report any unusual symptoms, such as dizziness, muscle stiffness, or confusion, immediately

Important Safety Information about Nozinan Injection

• Use only when prescribed by a qualified healthcare provider
• Not suitable for individuals with severe liver disease or hypersensitivity to phenothiazines
• Avoid alcohol or other CNS depressants while receiving treatment
• May cause low blood pressure; patients should avoid sudden position changes
• Regular monitoring may be needed for heart rhythm, liver function, and blood pressure
• Inform your healthcare provider of all medications being taken to prevent interactions

Fact Table

 

Facts	Details
Brand Name	Nozinan Injection
Generic Name	Levomepromazine Hydrochloride
Drug Class	Phenothiazine antipsychotic and sedative
Dosage Form	Injectable solution
Route of Administration	Intramuscular (IM) or Intravenous (IV)
Composition	Each mL contains 25 mg Levomepromazine Hydrochloride and excipients such as sodium chloride and water for injection
Indications / Uses	– Management of severe pain in palliative care – Treatment of agitation, anxiety, and restlessness in terminal illness – Control of severe nausea and vomiting – Sedation prior to medical procedures
Mechanism of Action	Levomepromazine blocks dopamine (D₂), histamine (H₁), and serotonin (5-HT₂) receptors, producing antipsychotic, sedative, antiemetic, and analgesic effects.
Onset of Action	Within 30-60 minutes (IM); faster via IV route
Duration of Action	8-12 hours, depending on dose and patient response
Dosage Range	Typically 6.25-25 mg IM/IV every 4-8 hours as needed (adjusted per clinical response)
Special Considerations	– Use the lowest effective dose to minimize sedation – Titrate carefully in elderly or frail patients – Monitor for orthostatic hypotension and ECG changes
Contraindications	– Known hypersensitivity to phenothiazines – Severe hepatic impairment – Bone marrow suppression – Coma or CNS depression from alcohol or sedatives
Precautions	– Use with caution in patients with cardiovascular disease, epilepsy, Parkinson’s disease, or glaucoma – May potentiate effects of CNS depressants and antihypertensives
Common Side Effects	Drowsiness, dry mouth, constipation, low blood pressure, blurred vision, dizziness
Drug Interactions	Additive effects with opioids, benzodiazepines, alcohol, and antihypertensives
Storage Conditions	Store below 25°C; protect from light; do not freeze
Prescription Status	Prescription-only medication

Common Side Effects

Like all medications, Nozinan Injection (Levomepromazine Hydrochloride) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Drowsiness or sedation
• Dry mouth
• Low blood pressure (especially when standing)
• Constipation
• Blurred vision

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Nozinan Injection (Levomepromazine Hydrochloride)?

You can order Nozinan Injection (Levomepromazine Hydrochloride) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.