Kayexalate (Sodium Polystyrene Sulfonate)

Kayexalate
Sodium Polystyrene Sulfonate

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Generic Equivalents   What's the difference?
Sodium Polystyrene Sulfonate
Sodium Polystyrene Sulfonate

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Kayexalate (Sodium Polystyrene Sulfonate)

Kayexalate (Sodium Polystyrene Sulfonate)

Kayexalate (Sodium Polystyrene Sulfonate) is a prescription medication primarily used to treat hyperkalemia, a condition characterized by high levels of potassium in the blood. This medicine works by exchanging sodium ions for potassium ions in the intestines, helping to lower the potassium levels in the body.

Why Choose Kayexalate (Sodium Polystyrene Sulfonate)?

  • Active Ingredient: Each dose of Kayexalate contains sodium polystyrene sulfonate, a powerful ion-exchange resin.
  • Formulations: Available in both oral suspension and powder forms. The powder can be mixed with water or syrup.
  • Onset of Action: Begins to lower potassium levels within 2 to 4 hours after administration, with the full effect seen in 24 to 48 hours.
  • Flexibility in Administration: Suitable for oral or rectal administration, providing options for patients with swallowing difficulties or nausea.
  • Long-term Efficacy: Ideal for both immediate and prolonged management of elevated potassium levels.

How to Use Kayexalate (Sodium Polystyrene Sulfonate)?

  • Oral Administration: For the powder form, dissolve the prescribed amount in a small amount of water or syrup. Stir thoroughly and consume immediately.
  • Rectal Administration: If prescribed as an enema, use as directed by a healthcare professional, ensuring proper technique to maximize efficacy.
  • Dosage: Dosage varies based on individual patient needs and potassium levels. Typical starting doses may range from 15g to 30g once or twice a day.
  • Duration of Treatment: Duration depends on the severity of hyperkalemia and response to the treatment. Regular monitoring of potassium levels is essential.

Important Safety Information about Kayexalate

  • Allergy Information: Avoid if allergic to sodium polystyrene sulfonate or any other ingredients in the product.
  • Contraindications: Not recommended for patients with hypokalemia (low potassium levels), obstructive bowel disease, or post-surgery intestinal anastomosis.
  • Drug Interactions: This may interfere with the absorption of other oral medications. A gap of at least 3 hours should be maintained between Kayexalate and other oral drugs.
  • Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.

Fact Table

 

Facts Details
Generic Name Sodium Polystyrene Sulfonate
Brand Name Kayexalate
Drug Type Ion-exchange resin
FDA Approval Approved for medical use
Indications Treatment of hyperkalemia (high blood potassium levels)
Available Forms Oral suspension, Powder for suspension
Administration Route Oral, Rectal
Standard Dosage Varies; typically 15g to 30g once or twice daily
Onset of Action Begins within 2-4 hours, with full effect in 24-48 hours
Contraindications Hypokalemia, obstructive bowel disease, recent bowel surgery
Common Side Effects Nausea, vomiting, constipation, diarrhea
Drug Interactions May affect the absorption of other oral medications
Special Precautions Careful use in patients with heart failure, hypertension
Storage Instructions Store at room temperature, away from heat and moisture
Packaging Available in containers for suspension and powder packets
Mechanism of Action Exchanges sodium ions for potassium ions in the intestines

Common Side Effects

Like all medications, Kayexalate (Sodium Polystyrene Sulfonate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Sodium retention

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Kayexalate (Sodium Polystyrene Sulfonate)?

You can order Kayexalate (Sodium Polystyrene Sulfonate) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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