Janumet (Metformin Hydrochloride/Sitagliptin Phosphate)

Janumet
Sitagliptin, Metformin HCl

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Janumet
Metformin Hydrochloride, Sitagliptin Phosphate

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Janumet (Metformin Hydrochloride/Sitagliptin Phosphate)

Janumet is a prescription medication that combines two powerful ingredients – Metformin Hydrochloride and Sitagliptin Phosphate – to manage blood sugar levels in adults with type 2 diabetes. This innovative dual-action formula is designed to improve blood sugar control and provide a convenient dosing option for those who need an extra boost in managing their diabetes.

Why Choose Janumet (Metformin Hydrochloride/Sitagliptin Phosphate)?

  • Dual-Action Control: Janumet uniquely combines Metformin and Sitagliptin, two widely prescribed medications for type 2 diabetes, to effectively lower blood sugar levels.
  • Convenient Dosing: Simplify your diabetes management routine with Janumet’s combination therapy, reducing the number of pills you need to take daily.
  • Customized Treatment: Available in various dosages to meet individual patient needs and doctor recommendations.
  • Metformin Hydrochloride: Works by decreasing glucose production in the liver and improving your body’s sensitivity to insulin, thus reducing the amount of sugar absorbed from food.
  • Sitagliptin Phosphate: Works by regulating the levels of insulin your body produces after eating.

How to use Janumet (Metformin Hydrochloride/Sitagliptin Phosphate)?

  • Take Janumet as prescribed by your healthcare provider.
  • Can be taken with or without food.
  • Swallow the tablet whole with water.
  • Do not crush, chew, or break the tablet.

Important Safety Information about Janumet

  • Not for the treatment of type 1 diabetes or diabetic ketoacidosis.
  • Not recommended for patients with severe kidney problems.
  • Your doctor should perform blood tests before starting and during treatment to monitor kidney function.
  • If you have had pancreatitis (inflammation of the pancreas), it is unknown if you have a higher chance of getting it while taking Janumet.

Fact Table

 

Facts Details
Generic Name Metformin Hydrochloride/Sitagliptin Phosphate
Brand Name Janumet
Drug Class – Metformin: Biguanide
– Sitagliptin: Dipeptidyl Peptidase-4 (DPP-4) Inhibitor
Indications Management of blood sugar levels in adults with type 2 diabetes
Dosage Forms Oral Tablets
Common Dosages – Janumet 50 mg/500 mg – Janumet 50 mg/1000 mg
Mechanism of Action – Metformin: Decreases hepatic glucose production, decreases intestinal absorption of glucose, improves insulin sensitivity – Sitagliptin: Increases levels of incretin hormones, enhances glucose-dependent insulin secretion, decreases glucagon secretion in the liver
Administration With or without food
Common Side Effects Nausea, diarrhea, headache, nasopharyngitis
Precautions Not for type 1 diabetes or diabetic ketoacidosis, monitor kidney function
Drug Interactions Risk of hypoglycemia with insulin and sulfonylureas; may need dose adjustment for drugs affected by kidney function changes

Common Side Effects

Like all medications, Janumet (Metformin Hydrochloride/Sitagliptin Phosphate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Nausea
  • Diarrhea
  • Headache
  • Common Cold
  • Hypoglycemia (Low Blood Sugar)

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Janumet (Metformin Hydrochloride/Sitagliptin Phosphate)?

You can order Janumet (Metformin Hydrochloride/Sitagliptin Phosphate) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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