Invega Sustenna (Paliperidone Palmitate)
Invega Sustenna (Paliperidone Palmitate)
Invega Sustenna (Paliperidone Palmitate) is a long-acting injectable antipsychotic used to treat schizophrenia and schizoaffective disorder in adults. It is given by a healthcare professional once a month, providing steady medication levels and reducing the need for daily pills. This helps improve treatment adherence and supports long-term stability.Why Choose Invega Sustenna (Paliperidone Palmitate)?
- Provides once-monthly dosing for convenience and consistency.
- Helps reduce symptoms of schizophrenia and schizoaffective disorder.
- Supports treatment adherence by eliminating daily oral dosing.
- Delivers a steady release of medication over time.
- May help lower the risk of relapse with ongoing treatment.
How to Use Invega Sustenna (Paliperidone Palmitate)?
- Invega Sustenna is administered only by a healthcare professional as an intramuscular injection.
- Initial doses are usually given in the deltoid (shoulder) muscle, followed by monthly injections.
- Attend all scheduled appointments to maintain consistent treatment.
- Do not self-inject or adjust your dosing schedule without medical advice.
- Inform your doctor about any other medications or health conditions before starting treatment.
Important Safety Information about Invega Sustenna
- Not recommended for individuals with a known allergy to paliperidone, risperidone, or any ingredients in the injection.
- May cause an increase in blood sugar, cholesterol, and weight gain.
- Can affect heart rhythm; caution is advised for patients with heart conditions.
- Use carefully in patients with a history of seizures, low white blood cell count, or kidney problems.
Fact Table
| Facts | Details |
| Brand Name | Invega Sustenna |
| Generic Name | Paliperidone Palmitate |
| Drug Class | Atypical antipsychotic (long-acting injectable) |
| Dosage Forms | Extended-release injectable suspension (IM injection) |
| Route of Administration | Intramuscular (IM) injection |
| Recommended Injection Sites | Initial doses: Deltoid muscle (upper arm); Maintenance doses: Deltoid or gluteal muscle |
| Indications (Uses) | - Schizophrenia in adults - Schizoaffective disorder in adults |
| Mechanism of Action | Paliperidone is an active metabolite of risperidone. It works by antagonizing dopamine D2 and serotonin 5-HT2A receptors, helping balance neurotransmitters linked to mood, thought, and behavior. |
| Onset of Action | Therapeutic levels achieved after initiation doses (Day 1 and Day 8) |
| Common Side Effects | - Injection site reactions (pain, redness) - Weight gain - Drowsiness - Dizziness - Insomnia - Akathisia (restlessness) - Headache |
| Contraindications | - Known hypersensitivity to paliperidone, risperidone, or any formulation components |
| Warnings & Precautions | - Not approved for dementia-related psychosis (↑ risk of death in elderly) - Monitor for metabolic changes (weight, glucose, lipids) - Caution in patients with cardiovascular disease or seizure history |
| Drug Interactions | - Caution with drugs affecting QT interval - CNS depressants - Carbamazepine (may lower paliperidone levels) |
| Storage | Store at room temperature (25°C/77°F); excursions permitted 15–30°C (59–86°F). Do not freeze. |
Common Side Effects
Like all medications, Invega Sustenna (Paliperidone Palmitate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.- Injection site reactions (pain, redness, or swelling)
- Drowsiness or dizziness
- Weight gain
- Restlessness or tremors
- Headache
- Nausea
How Can You Buy Invega Sustenna (Paliperidone Palmitate)?
You can order Invega Sustenna (Paliperidone Palmitate) using these methods on our website:- Order Online
- Order by Phone
- Order by Fax
- Order your refills
