Ikorel (Nicorandil)
Ikorel (Nicorandil)
Ikorel (Nicorandil) is a prescription treatment used to manage angina pectoris (chest pain caused by reduced blood flow to the heart). It works by relaxing and widening blood vessels, improving oxygen supply to the heart, and reducing strain during physical activity or stress.
Why Choose Ikorel (Nicorandil)?
- Helps relieve and prevent angina attacks
- Improves blood flow to the heart muscle
- Reduces frequency and intensity of chest pain
- Can enhance exercise tolerance in patients with angina
- Provides dual action: nitrate-like effect and potassium channel activation
How to Use Ikorel (Nicorandil)?
- Take Ikorel exactly as prescribed by your healthcare provider.
- Swallow tablets whole with water, preferably at the same time each day.
- Do not crush or chew the tablets.
- Continue taking the medicine even if you feel well, unless advised otherwise.
- If you miss a dose, take it as soon as possible, but skip it if it’s almost time for your next one. Do not double-dose.
Important Safety Information about Ikorel
- Not suitable for patients with severe low blood pressure, acute heart failure, or cardiogenic shock.
- Avoid combining with medications such as phosphodiesterase inhibitors (e.g., sildenafil), as this may cause a dangerous drop in blood pressure.
- Inform your doctor if you have a history of ulcers, eye problems, or other vascular conditions.
- Regular monitoring may be required for blood pressure and overall heart function.
- Do not stop treatment suddenly without consulting your healthcare professional.
Fact Table
| Facts | Details |
| Generic Name | Nicorandil |
| Brand Name(s) | Ikorel |
| Drug Class | Vasodilator (Nitrate-like + Potassium Channel Opener) |
| Indication | Treatment and prevention of angina pectoris (chest pain due to coronary artery disease) |
| Mechanism of Action | – Relaxes and widens blood vessels (vasodilation) – Improves blood flow and oxygen supply to the heart – Reduces cardiac workload |
| Dosage Forms | Oral tablets |
| Administration | – Take orally with water – Can be taken with or without food – Swallow whole, do not crush or chew |
| Onset of Action | Within 30–60 minutes |
| Duration of Action | Around 12 hours (depends on dose and patient response) |
| Common Side Effects | – Headache – Flushing – Dizziness or lightheadedness – Nausea – Fatigue |
| Contraindications | – Severe hypotension – Cardiogenic shock – Acute pulmonary edema – Concurrent use with PDE-5 inhibitors (e.g., sildenafil, tadalafil) |
| Precautions | – Use with caution in patients with history of ulcers or low blood pressure – May impair ability to drive or operate machinery due to dizziness – Avoid abrupt discontinuation |
| Drug Interactions | – PDE-5 inhibitors (sildenafil, vardenafil, tadalafil) – Other vasodilators or antihypertensives (may enhance hypotension) – Alcohol (increases risk of dizziness, fainting) |
| Storage Conditions | Store at room temperature (15–25°C), protect from moisture and light |
Common Side Effects
Like all medications, Ikorel (Nicorandil) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Headache (often improves with continued use)
- Flushing or warmth in the face
- Dizziness or lightheadedness
- Nausea or upset stomach
- Fatigue or weakness
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Ikorel (Nicorandil)?
You can order Ikorel (Nicorandil) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
