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Heartgard Plus-Brown(L) (Ivermectin/ Pyrantel Pamoate)

 

Heartgard Plus-Brown(L) (Ivermectin/ Pyrantel Pamoate)

Heartgard Plus Brown is a monthly chewable preventive formulated for large dogs (51–100 lbs) to protect against heartworm disease and intestinal parasites. It combines ivermectin and pyrantel pamoate to stop heartworm larvae transmitted by mosquito bites and to treat and control roundworms and hookworms. The soft, beef-flavored chew is easy to administer and designed to be taken once monthly all year round for continued protection.

Why Choose Heartgard Plus-Brown(L) (Ivermectin/ Pyrantel Pamoate)?

  • Protects large dogs (51–100 lbs) from deadly heartworm disease
  • Treats and controls roundworms and hookworms
  • Tasty beef chew, easy to give like a treat
  • Convenient once-a-month dosing
  • Vet-recommended prevention that starts working quickly
  • Helps maintain long-term parasite protection with regular use

How to Use Heartgard Plus-Brown(L) (Ivermectin/ Pyrantel Pamoate)?

  • Confirm your dog weighs between 51–100 lbs before administering the Brown (L) dose.
  • Give one chewable tablet by mouth once every 30 days.
  • Offer like a treat or mix with a small amount of food to ensure full consumption.
  • Continue dosing year-round, even in colder months.
  • If a dose is missed, give it as soon as you remember and resume your monthly schedule.
  • Have your dog tested for heartworms annually as recommended by your veterinarian.

Important Safety Information about Heartgard Plus-Brown(L)

  • For dogs only, not for cats or other animals.
  • Dogs must be tested heartworm-negative before starting Heartgard Plus.
  • Use the correct chew based on your dog’s weight to avoid under- or overdosing.
  • Not recommended for dogs with a history of ivermectin sensitivity.
  • Store product in a cool, dry place and keep out of reach of children.
  • Consult your veterinarian if your dog is pregnant, breeding, or lactating.

Fact Table

 
Facts Details
Brand Name Heartgard Plus
Strength / Color Brown (L)
Weight Range For large dogs 51-100 lbs (23-45 kg)
Active Ingredients Ivermectin / Pyrantel Pamoate
Parasites Prevented / Treated - Prevents heartworm disease (Dirofilaria immitis) - Treats & controls roundworms (Toxocara canis, Toxascaris leonina) - Treats & controls hookworms (Ancylostoma caninum, Uncinaria stenocephala)
Form Chewable tablet (beef-flavored)
Administration Oral - given once monthly
Minimum Age Safe for dogs 6 weeks and older
Prescription Required Yes (veterinary prescription)
Dosing Frequency Once every 30 days (year-round)
How It Works - Ivermectin eliminates heartworm larvae before they mature - Pyrantel pamoate targets and eliminates roundworms & hookworms
Package Options 6-pack and 12-pack
Safe Use Recommendations Use correct dosage based on weight; regular annual heartworm testing recommended
Storage Instructions Store at room temperature; keep in sealed blister pack until use
Safety Notes Dogs must be heartworm-negative before starting therapy
Common Side Effects Mild digestive upset, drooling, lethargy, decreased appetite (rare)
Not For Use In Dogs under 51 lbs for this size; not for cats
Additional Benefits Easy treat-like administration improves owner compliance

Common Side Effects

Like all medications, Heartgard Plus-Brown(L) (Ivermectin/ Pyrantel Pamoate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
  • Mild digestive upset (vomiting, diarrhea)
  • Lethargy or decreased appetite
  • Temporary drooling after dosing
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Heartgard Plus-Brown(L) (Ivermectin/ Pyrantel Pamoate)?

You can order Heartgard Plus-Brown(L) (Ivermectin/ Pyrantel Pamoate) using these methods on our website:
  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills
Visit our How to order page.
Dr. Conor Sheehy, PharmD, BCPS

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.

Please note that due to government rules and regulations, orders may not exceed 3 months in supply.
Please call 1-800-258-0477 or email us if you have any questions or concerns.