Harvoni (Ledipasvir/ Sofosbuvir)

Harvoni (Ledipasvir/ Sofosbuvir)

Harvoni, a breakthrough in Hepatitis C treatment, combines Ledipasvir and Sofosbuvir in one tablet. It is primarily intended to treat chronic Hepatitis C virus (HCV) genotypes 1, 4, 5, and 6 in adults and children over the age of 3. Harvoni’s once-daily oral regimen provides a cure for many patients suffering from this chronic illness, opening a new age of HCV treatment with its high cure rates and simpler therapy schedule.

Why Choose Harvoni (Ledipasvir/ Sofosbuvir)?

• High Cure Rate: Harvoni has been reported to cure up to 99% of individuals with Hepatitis C genotypes 1, 4, 5, and 6 in just 12 weeks of treatment, including many patients without or with compensated cirrhosis.
• Single Tablet Regimen: Harvoni is a single-tablet regimen that combines two antiviral drugs, Ledipasvir and Sofosbuvir, eliminating the need for interferon or ribavirin for the majority of patients.
• Reduced Treatment Duration: For many patients, treatment can be finished in 8 to 12 weeks, which is much shorter than previous treatment alternatives.
• Well-Tolerated: Harvoni is usually well-tolerated, with the most frequent adverse effects being fatigue and headache.

How to Use Harvoni (Ledipasvir/ Sofosbuvir)?

• Harvoni is taken once a day, with or without meals.
• You must take Harvoni exactly as directed by your healthcare professional for the whole duration of the therapy, even if your symptoms improve.
• Do not change your dose or stop taking Harvoni without first consulting your doctor.

Important Safety Information about Harvoni

• Before beginning Harvoni, tell your doctor about all of your medical conditions, especially whether you have hepatitis B, liver disorders other than hepatitis C, or have undergone a liver transplant.
• Inform your doctor about all of the medications you take, including prescription and over-the-counter medications, vitamins, and herbal supplements. Harvoni can interact with other medications, resulting in serious side effects.
• The most common Harvoni side effects are weariness and headache. Serious adverse effects are uncommon but may occur.

Fact Table

 

Facts	Details
Generic Name	Ledipasvir/ Sofosbuvir
Brand Name	Harvoni
Approved By	FDA (Food and Drug Administration)
Date of Approval	October 2014
Indications	Treatment of chronic Hepatitis C virus (HCV) genotypes 1, 4, 5, and 6 in adults and children over 3 years of age
Dosage Form	Oral tablet
Strengths	90 mg Ledipasvir/400 mg Sofosbuvir
Recommended Dosage	One tablet daily
Treatment Duration	8, 12, or 24 weeks, depending on patient-specific factors including the presence of cirrhosis, treatment history, and viral genotype
Mechanism of Action	Ledipasvir is an NS5A inhibitor, and Sofosbuvir is a nucleotide polymerase inhibitor. Together, they prevent the hepatitis C virus from multiplying and spreading.
Common Side Effects	Fatigue, headache
Drug Interactions	Significant interactions with amiodarone, anticonvulsants, antituberculous agents, herbal supplements like St. John’s Wort, and HIV antiviral regimens
Contraindications	Known hypersensitivity to Ledipasvir, Sofosbuvir, or any component of the formulation
Pregnancy Category	Category B (No evidence of risk in humans)

Common Side Effects

Like all medications, Harvoni (Ledipasvir/ Sofosbuvir) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Fatigue
• Headache
• Nausea
• Insomnia
• Cough

If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Harvoni (Ledipasvir/ Sofosbuvir)?

You can order Harvoni (Ledipasvir/ Sofosbuvir) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.