Canada Post & FedEx shipping 
Glucotrol XL (Glipizide)
Glucotrol XL (Glipizide)
Glucotrol XL (Glipizide) is an extended-release oral medication designed to help manage blood sugar levels in adults with type 2 diabetes. It works by stimulating the pancreas to produce insulin, improving blood sugar control when combined with a proper diet and exercise regimen. This once-daily tablet provides consistent glucose management throughout the day.
Why Choose Glucotrol XL (Glipizide)?
- Effective Blood Sugar Control: Helps regulate glucose levels in individuals with type 2 diabetes.
- Convenient Dosing: Extended-release formula allows for once-daily administration.
- Improved Insulin Response: Stimulates insulin production for better glucose uptake.
- Supports Diabetes Management: Aids in preventing long-term complications associated with high blood sugar.
How to Use Glucotrol XL (Glipizide)?
- Follow Prescription Instructions: Take exactly as directed by your healthcare provider, preferably with breakfast.
- Maintain a Consistent Routine: Take Glucotrol XL at the same time each day to ensure stable blood sugar levels.
- Combine with Diet and Exercise: Enhance the medication’s effectiveness by adhering to a healthy lifestyle.
- Monitor Blood Sugar Levels: Regularly check glucose levels and report any significant changes to your doctor.
- Avoid Crushing or Chewing: Swallow the tablet whole to preserve its extended-release properties.
Important Safety Information about Glucotrol XL
- Hypoglycemia Risk: Be cautious of low blood sugar symptoms such as dizziness, sweating, or shakiness. Carry a sugar source for emergencies.
- Avoid Alcohol: Drinking alcohol may increase the risk of hypoglycemia or adverse reactions.
- Inform Your Doctor: Disclose all medications, supplements, and medical conditions before starting Glucotrol XL.
- Not for Type 1 Diabetes: This medication is not suitable for individuals with type 1 diabetes or diabetic ketoacidosis.
Fact Table
| Facts | Details |
| Brand Name | Glucotrol XL |
| Generic Name | Glipizide |
| Drug Class | Sulfonylureas |
| Formulation | Extended-Release Tablet |
| Strengths Available | 2.5 mg, 5 mg, 10 mg |
| Indications | Type 2 Diabetes Mellitus |
| Mechanism of Action | Stimulates insulin secretion from pancreatic beta cells. |
| Dosage and Administration | – Initial dose: 5 mg once daily with breakfast or first main meal. – Maximum dose: 20 mg once daily. |
| Duration of Action | 24 hours |
| Onset of Action | 1–3 hours |
| Peak Effect | 6–12 hours |
| Common Side Effects | – Hypoglycemia – Dizziness – Nausea – Headache – Weakness |
| Drug Interactions | – Increased risk of hypoglycemia with insulin, alcohol, or beta-blockers
– Reduced efficacy with corticosteroids, diuretics, or thyroid medications |
| Storage Conditions | Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light. |
| Special Precautions | – Use cautiously in patients with liver or kidney impairment. – Avoid in severe hypoglycemic risk patients. |
Common Side Effects
Like all medications, Glucotrol XL (Glipizide) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Hunger
- Sweating
- Nausea
- Diarrhea
- Dizziness
- Fatigue
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Glucotrol XL (Glipizide)?
You can order Glucotrol XL (Glipizide) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
4 INSTALLMENTS, 6 WEEKS, 0% INTEREST
PharmaServe now offers you the option to make 4-interest-free payments by credit card once your order is confirmed using
Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
OZEMPIC: Huge price drop limited stock, limited time opportunity. 
MOUNJARO (12.5mg): Save up to 70% Use code MN12MG for an additional 10% off for 12.5mg. Chat now to order and save up to $90 or