Genvoya (Emtricitabine/ Cobicistat/ Elvitegravir/ Tenofovir Alafenamide)

Genvoya is a once-daily prescription treatment for HIV-1 infection. It combines four active ingredients, Emtricitabine, Cobicistat, Elvitegravir, and Tenofovir Alafenamide, into a single tablet designed to simplify therapy and help maintain viral suppression. By targeting the virus at multiple stages, Genvoya helps reduce HIV levels in the blood, supporting better long-term management and improved quality of life.

Why Choose Genvoya (Emtricitabine/ Cobicistat/ Elvitegravir/ Tenofovir Alafenamide)?

Single daily tablet, reducing pill burden.
Helps achieve and maintain an undetectable HIV viral load.
Designed with Tenofovir Alafenamide (TAF), which may have less impact on kidney function and bone density compared to older formulations.
Often prescribed for adults and adolescents (aged 12 and older) who are starting treatment or switching from other regimens.
Backed by clinical evidence supporting effectiveness and tolerability.

How to Use Genvoya (Emtricitabine/ Cobicistat/ Elvitegravir/ Tenofovir Alafenamide)?

Take one tablet by mouth once daily, with food.
Swallow whole, do not crush, chew, or split.
Take at the same time each day to maintain steady medication levels.
Inform your healthcare provider about all other medicines, supplements, or herbal products you take.
Do not stop taking Genvoya without medical guidance, as it may affect viral control.

Important Safety Information about Genvoya

Not recommended for individuals with severe liver impairment.
May interact with certain medicines (anticonvulsants, antimycobacterials, St. John’s Wort, etc.), consult your provider.
Kidney function should be monitored periodically during treatment.
Risk of lactic acidosis and severe liver problems, though rare, should be considered.
Do not use in combination with other antiretroviral drugs containing similar ingredients.

Fact Table

Facts	Details
Brand Name	Genvoya
Generic Name	Emtricitabine / Cobicistat / Elvitegravir / Tenofovir Alafenamide
Drug Class	Antiretroviral Combination (Integrase Strand Transfer Inhibitor + NRTIs + Pharmacokinetic Enhancer)
Formulation	Single tablet regimen
Route of Administration	Oral
Recommended Dose	1 tablet once daily, with food
Indications	Treatment of HIV-1 infection in adults and pediatric patients ≥12 years old (and weighing ≥35 kg), who are treatment-naïve or virologically suppressed on a stable regimen
Contraindications	• Severe liver impairment (Child-Pugh Class C) • Concurrent use with certain drugs (e.g., rifampin, carbamazepine, phenobarbital, phenytoin, St. John’s Wort)
Warnings & Precautions	• Lactic acidosis and severe hepatomegaly with steatosis (rare) • Worsening of hepatitis B virus (HBV) infection after discontinuation • Renal toxicity risk, monitor renal function • Possible drug-drug interactions due to cobicistat inhibition of CYP3A
Common Side Effects	Nausea, diarrhea, headache, fatigue, dizziness, mild rash
Drug Interactions	Avoid strong CYP3A inducers (e.g., rifampin, St. John’s Wort) - Adjustments/monitoring may be required with anticonvulsants, antimycobacterials, anticoagulants, and certain antivirals
Monitoring Parameters	• HIV viral load and CD4 counts • Liver function tests • Renal function (serum creatinine, eGFR) • HBV co-infection status before initiation
Storage Conditions	Store at room temperature (20°C to 25°C / 68°F to 77°F). Keep in original container, tightly closed, and protect from moisture.

Common Side Effects

Like all medications, Genvoya (Emtricitabine/ Cobicistat/ Elvitegravir/ Tenofovir Alafenamide) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

Nausea
Diarrhea
Headache
Fatigue
Dizziness

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Genvoya (Emtricitabine/ Cobicistat/ Elvitegravir/ Tenofovir Alafenamide)?

You can order Genvoya (Emtricitabine/ Cobicistat/ Elvitegravir/ Tenofovir Alafenamide) using these methods on our website:

Order Online
Order by Phone
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Order your refills

Visit our How to order page.